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EXPLORE NORTHEASTERN

Research Groups

Associate Professor Jeffrey Agar
We develop mass spectrometry tools for studying neurologic disease, including single-cell imaging, top-down mass spectrometry, and a new class of crosslinkers that we are developing into protein stabilizing drugs.

Professor Heather Clark
We create novel nanoscale probes to image and measure the chemistry of the body, with a particular focus on the signaling in the brain and nervous system.

Assistant Professor Leila Deravi
We work at the interface of bio-analytical chemistry, materials science, and design, where we investigate fundamental mechanisms behind systems in biology and use our understanding to design new classes of protein-based biomaterials that may interface with or enhance the performance of humans.

Distinguished Professor John R. Engen
We use hydrogen exchange and mass spectrometry (HX MS) as our core technology to probe protein conformation, conformational changes, dynamics, protein folding and the effects of binding

Professor Roger W. Giese
We focus on testing biosamples such as breath, placenta and urine for small molecules by mass tag mass spectrometry, including metabolome and DNA adductome analyses.

Associate Professor Alexander Ivanov
We develop microscale liquid phase separation- and mass spectrometry (MS)-based molecular characterization technologies for deep proteomic profiling of limited biological and clinical samples; detailed analysis of proteins, including isoforms, modifications, and non-covalent complexes; and isolation and omics profiling of exosomes and other extracellular microvesicles.

Assistant Professor of Bioengineering Nikolai Slavov
We develop methods for quantifying proteins in single cells at high-throughput. We apply these methods to analyze protein networks at single-cell resolution and link the network states to functional phenotypes, such as cell type and differentiation potentials. Furthermore, we characterize the mechanisms by which specialized ribosomes regulate protein synthesis.

Sy and Laurie Sternberg Interdisciplinary Associate Professor Olga Vitek
We develop statistical methods and software for quantitative mass spectrometry-based investigations, to characterize the components of the biological systems, their function, and their relevance to disease.

Professor Sunny Zhou
Research in my laboratory, aka SunnyLand, centers on the chemistry and analysis of proteins, including hybrid modality engineering, developing new methodologies and creating better therapeutics.

 

Emeriti

Professor William S. Hancock

Professor Barry L. Karger

Professor Paul Vouros