Research Groups
Director
Sy and Laurie Sternberg Interdisciplinary Associate Professor Olga Vitek
We develop statistical methods and software for quantitative mass spectrometry-based investigations, to characterize the components of the biological systems, their function, and their relevance to disease.
Barnett Faculty Fellows
Associate Professor Jeffrey Agar
We develop mass spectrometry tools for studying neurologic disease, including single-cell imaging, top-down mass spectrometry, and a new class of crosslinkers that we are developing into protein stabilizing drugs.
Professor Jared Auclair
The unique offerings at BATL meet the needs of multiple and diverse scientific and medical stakeholders, from early discovery and development in industry to experiential training, from global regulatory convergence to use-inspired research.
Professor Roger W. Giese
We focus on testing biosamples such as breath, placenta and urine for small molecules by mass tag mass spectrometry, including metabolome and DNA adductome analyses.
Associate Professor Alexander Ivanov
We develop microscale liquid phase separation- and mass spectrometry (MS)-based molecular characterization technologies for deep proteomic profiling of limited biological and clinical samples; detailed analysis of proteins, including isoforms, modifications, and non-covalent complexes; and isolation and omics profiling of exosomes and other extracellular microvesicles.
Professor Roman Mantesch
Our research addresses various aspects of medicinal chemistry related to optimization of anti-malarial, anti-leishmanial, and anti-bacterial agents, as well as developing and applying LC/MS-based approaches facilitating synthetic and medicinal chemistry.
Associate Professor Nikolai Slavov
We develop methods for quantifying proteins in single cells at high-throughput. We apply these methods to analyze protein networks at single-cell resolution and link the network states to functional phenotypes, such as cell type and differentiation potentials. Furthermore, we characterize the mechanisms by which specialized ribosomes regulate protein synthesis.
Assistant Professor Zhenyu Tian
We develop and apply chromatography-mass spectrometry methods to analyze emerging organic contaminants in environmental and biological samples, assessing the risks to human health and the ecosystem.
Barnett Affiliated Faculty Fellows
Associate Professor Leila Deravi
We work at the interface of bio-analytical chemistry, materials science, and design, where we investigate fundamental mechanisms behind systems in biology and use our understanding to design new classes of protein-based biomaterials that may interface with or enhance the performance of humans.
Professor Predrag Radivojac
We study protein structure, dynamics, expression, and function by integrating various forms of molecular and genetic data and develop machine learning approaches to make predictions. Understanding protein function is a step towards understanding molecular mechanisms of human genetic disease.
Emeriti
Professor William S. Hancock
Professor Barry L. Karger
Professor Paul Vouros