The Science of Tomorrow

Society significantly benefits from scientific research, but it wouldn’t be possible without generous contributions from public and private sources.

This page is a testament to that support. With it, Northeastern’s College of Science has cultivated a dynamic landscape of research activity. Through a culture that emphasizes entrepreneurship, our exceptional faculty, staff, and student researchers are able to maximize the impact of their work.

The grants listed below are a preview of the science and scientists of tomorrow, who probe single cells, the outer limit of particle physics, and everything in between.

03/19/2024

Dan Distel

Marine and Environmental Sciences
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Sponsor: Cell Signaling Technology, 507764

Annual Environmental and Social Responsibility Grant: Ocean Genome Legacy Student Research in DNA Preservation

This grant will support OGL's long running and successful Student Research in DNA Preservation Program, providing funds for experiments to improve the quality of DNA extracted from frozen biological materials. Freezing at ultra-cold temperatures (>80°C) is considered the "gold standard" for preserving DNA in tissue samples. However, OGL's co-op student researchers noticed that DNA extracted from frozen tissue often appears highly degraded. OGL students hypothesized that this may be due to tissue thawing, which is required during DNA extraction. Even if this thawing lasts just a few seconds, there might be enough time for DNase enzymes to break the DNA down. To prevent this damage, OGL students are testing what happens if frozen tissue is thawed overnight in chilled liquid preservatives instead of extracting DNA directly from frozen tissue. If successful, this could save millions of frozen samples in collections worldwide that might otherwise not be useful for genomic research.

03/14/2024

Randall Hughes, Sara Constantino, Laura Kuhl

MES
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Sponsor: National Science Foundation, Award Number: 2322178

CIVIC-FA Track A: Kickstarting A Youth-Centered Green Economy For The Environmental Justice Community Of East Boston

This research involves understanding how underserved communities get actively engaged in making the transition to a vibrant green economy with improved environmental conditions and community resilience to climate change. To accomplish this goal, the research engages local youth in constructive and productive activities involving urban farming, coastal restoration, and social science-driven community engagement via a non-profit community entity (Eastie Farm).

03/13/2024

Art Kramer and Chuck Hillman

Psychology
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Sponsor: NIH/NIA

Breaking prolonged sitting with high intensity interval training to improve cognitive and brain health in older adults

Capitalizing on Physical Activity intensity as the major limiting factor in peripheral catecholamine increase, we propose a randomized crossover trial to compare 2 conditions lasting 3.5 h each: sitting interrupted by 6-min HIIT every 30 min (HIIT Breaks), and sitting interrupted by 6-min social interactions (SIT) to address 3 aims: (i) to assess feasibility, acceptability, fidelity, and safety of HIIT Breaks to improve neurocognitive function; (ii) to quantify the differences between conditions in the change in P3b amplitude and latency; (iii) to explore the differences between conditions in attentional control, episodic memory, and functional connectivity (FC) of the frontoparietal and default mode networks. Our long-term objective is to test the chronic effects of HIIT breaks on the integrity of the locus coeruleus, frontoparietal function, and cognitive functions affected by aging and AD in cognitively healthy and cognitively impaired seniors.

03/12/2024

Laszlo Barabasi

Physics
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Sponsor: NSF 2243104; University of Michigan PTE: SUBK00018203

Center for Complex Particle Systems (Compass)

Robustness under variable conditions is an essential property that biological organisms and human networks acquire by adopting a dynamic hierarchical structure. Moreover, complex organization spontaneously emerges from simple constitutents if they are numerous, strongly interacting and diverse. A nearly identical set of attributes is characteristic of colloidal particles, ranging in size from nanometers to microns. The Center for Complex Particle Systems (COMPASS) will understand, develop, and exploit this paradigm in systems of strongly interacting and polydisperse colloidal particles. In doing so, we expect to fundamentally transform the discipline of colloidal science and to engender transformative changes in multiple areas of engineering and particle-based manufacturing.

03/12/2024

Jing-Ke Weng

Chemistry and Chemical Biology
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Sponsor: Food Allergy Science Initiative (FASI)

The role of phytochemicals in food allergy

This project investigates the role of phytochemicals in food allergies, focusing on identifying plant secondary metabolites that influence allergic reactions and developing potential therapeutics for food allergies. Jing-Ke Weng's lab aims to advance understanding of food allergy causes and mechanisms through interdisciplinary research on plant chemistry and its interaction with the human immune system, with the ultimate goal of creating new treatments for food allergies.

03/12/2024

Charles Hillman

Psychology
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Sponsor: R01 AG083156

Examining the Persistence of Neurocognitive Benefits of Exercise

In this 5-year follow-up to the IGNITE exercise intervention study we will examine whether exercise has a delayed or protracted benefit to neurocognitive outcomes including Alzheimer’s disease neuropathology. We will also examine whether we can predict long-term exercise engagement by utilizing the rich biological and psychological data from IGNITE.

03/12/2024

Srinivas Sridhar

Physics
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Sponsor: NIH NCI 2R25CA174650-11

CaNCURE: Cancer Nanomedicine Co-ops for Undergraduate Research Experiences

CaNCURE: Cancer Nanomedicine Co-ops for Undergraduate Research Experiences Program seeks to provide training and education in research at the interface of nanotechnology, cancer biology, and medicine to attract, retain, and encourage young scientists & engineers, particularly those from underrepresented minorities, to pursue careers in cancer research. The program will achieve this central aim by creating meaningful and rigorous research experiences mentored by outstanding academic and clinical researchers and supplemented with high-impact learning and professional development opportunities. The program combines Northeastern University’s model of co-op education with the outstanding cancer nanomedicine research infrastructure at Dana-Farber/Harvard Cancer Center to create an immersive and inclusive training environment for knowledge and skills acquisition for the next generation of cancer researchers.

03/12/2024

Ben Knudsen, Iva Halacheva, and Jose Perea

Mathematics
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Sponsor: NSF

Mid-Atlantic Topology Conference 2024

The Mid-Atlantic Topology Conference is a recurring regional topology meeting, previous iterations of which have been hosted at UVA, Johns Hopkins, and Penn. The latest iteration is planned for March 23–24, 2024 at Northeastern University. As in the past, the event will take a broad thematic focus and prioritize showcasing young researchers and those from underrepresented populations. The conference will highlight a broad selection of current directions in topology, including geometric group theory, geometric and topological data analysis, applied and computational topology, higher category theory, and motivic homotopy theory. The goal is to continue to capture and focus the momentum from a series of new hires in topology seen on the East Coast in recent years, and to provide regional researchers of all career stages and subdisciplines of topology with the opportunity to build community, discuss research, and gain exposure to new ideas.

03/11/2024

Jing-Ke Weng

Chemistry and Chemical Biology
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Sponsor: USDA

Discovery and engineering of plant branched cyclic peptide biosynthesis

Plants offer an enormous chemodiversity that is essential for discovering new medicines, with 25% of all FDA-approved drugs coming from plants. However, the production of plant-derived natural products faces significant challenges. Our research aims to explore the biosynthesis and bioengineering of lyciumins and moroidins, two classes of branched cyclic peptides with potential pharmaceutical applications. Lyciumins, inhibitors of the human angiotensin-converting enzyme, come from the Goji berry, while moroidins, derived from the Australian stinging tree, exhibit anti-mitotic activities suitable for cancer therapy. Both are ribosomally synthesized and post-translationally modified peptides (RiPPs) in plants, suggesting potential for enhanced chemical diversity and production. We propose to advance our understanding of RiPP diversity and biosynthesis, supporting new strategies for their engineering and application in medicine. 

02/20/2024

Lori Ferrins

Chemistry and Chemical Biology
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Sponsor: NIH AViDD Center Development Grant

Development of covalent SARS-CoV-2 papain-like protease inhibitors

There are two goals in this project, firstly, to continue to develop our advanced hit compound (disclosed here: doi: 10.1038/s41467-023-37254-w) to identify a lead suitable for in vivo proof of concept studies. Secondly, to develop novel methods to study the structural dynamics of both covalent inhibitors and PLpro active site structures enabling the development of more potent covalent inhibitors.

01/26/2024

Javier Apfeld

Biology
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Sponsor: Longevity Impetus grant (A-241530)

Engineering C. elegans worms to live more than a year

Can a worm that normally lives 15 days live a year? How much can we extend lifespan if we combine multiple interventions that extend lifespan on their own? We are excited to find out how plastic is the lifespan of C. elegans worms.

12/15/2023

Thiago dos Santos

Chemistry and Chemical Biology
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Sponsor: HHMI

Hanna H. Gray Fellow's Program Transition Award

Our group will study the proteins that build the bacterial cell envelope and develop mechanism-based inhibitors of these proteins to treat multidrug-resistant infections.

12/15/2023

Andreia Ionescu

Biology
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Sponsor: NIH

Growth plate cartilage stem cells for skeletal repair after injury

In this project, the investigators study the role of growth plate stem cells in hopes of gaining insights in the skeletal repair process after physeal injury in children. The results of the study will help bioengineering efforts directed towards growth plate cartilage regeneration.

12/01/2023

Sue Whitfield Gabrieli

Psychology
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Sponsor: Accord Family

Mindfulness Based Real-time fMRI Neurofeedback Intervention for Borderline Personality Disorder

In collaboration with McLean Hospital, this study aims to reduce the symptoms of Borderline Personality Disorder (BPD) in young adults by using real-time mindfulness-based neurofeedback during an fMRI scan. This technique helps augment mindfulness meditation by showing participants a visual display of their brain activity in the fMRI scanner. Participants will track BPD symptoms and mindfulness skills via ecological momentary assessment (EMA), which involves brief daily, smartphone-delivered surveys.

12/01/2023

Gabriela Garcia

Marine and Environmental Sciences
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Sponsor: TNC

Adaptation in the Amazon

The Adaptation in the Amazon Research Technician will work with PI Gabriela Garcia (MES and SPPUA) to support The Nature Conservancy’s global team to understand climate impacts and adaptation needs of communities in the Amazon region and how nature-based approaches can support equitable adaptation goals. They will support the selection, adaptation, implementation, and analysis of risk and vulnerability assessment in four countries (Brazil, Colombia, Peru, and Ecuador) of the Amazon region.

12/01/2023

Alexander Ivanov

Chemistry and Chemical Biology
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Sponsor: NIH
Biomedical Technology Development and Dissemination Center

Funded by an NIH P41 subaward, this project from the Biomedical Technology Development and Dissemination Center aims to translate native mass spectrometry (nMS) workflows for characterizing macromolecular complexes to biomedical research communities. The provided tools support both expert and non-expert users in integrating nMS with other structural biology techniques throughout the project. This initiative seeks to accelerate the production of models for complex protein machines and macromolecular structures, addressing challenges in standard structural biology and enhancing insights into cellular processes and human disease.

12/01/2023

Dima Krioukov

Physics
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Sponsor: NSF

CIF: Small: Projective limits of sparse graphs

This project aims to analyze and identify well-behaved graph limits for sparse random graph models, specifically focusing on influential models developed in the investigator's previous NSF-funded research related to real-world networks. The goal is to ensure that conclusions drawn from these models are realistic by verifying that their limits are graphides.

11/01/2023

Karen Quigley

Psychology
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Sponsor: Army Research Laboratory

Reconsidering context: Theory and Measurement

Self-reports of experience are most often quantified via anchored, Likert-type rating scales (e.g., using a scale from 0-5, where 0 is no fatigue and 5 is maximal fatigue). Raters change how they use such scales when their internal bodily state changes, making such scales poorly reliable and invalid under such conditions. The investigators have developed a new normalized self-report rating scale method in which people map specific prior autobiographical experiences to person-specific scale metrics. The researchers will compare metrics from the new scales to traditional Likert-type metrics. They also will use a well-known (and safe) immune challenge, a typhoid vaccine, to assess whether the new scale method provides more reliable and valid self-report outcomes across different bodily states. A new method is important for testing new drug or behavioral treatments when pre- and post-treatment ratings of experience (like fatigue) are used to determine whether a new treatment is effective.

09/28/2023

Tsuguo Aramaki

Physics
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Sponsor: NASA

A prototype flight for the GRAMS project

This grant is for the prototype balloon flight of the GRAMS (Gamma-Ray and AntiMatter Survey) Project. GRAMS mission aims to deliver unprecedented sensitivities to astrophysical observations with MeV gamma rays and indirect dark matter searches with antimatter using a cost-effective, large-scale LArTPC (Liquid Argon Time Projection Chamber) detector. We will build and optimize a small-scale detector, MiniGRAMS, and demonstrate its performance in the balloon flight scheduled in late 2025 or early 2026.

09/26/2023

Sijia Dong

Chemistry and Chemical Biology
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Sponsor: DOE

Framework for Converting Gate-Based Quantum Computing Models to Quantum Annealing Models for Large-Scale Electronic Structure and Dynamics Simulations

Simulating the electronic structure of molecular systems using noisy intermediate-scale quantum devices is one of the most promising applications of quantum computing. Large-scale electronic structure and dynamics simulations, such as excited-state simulations of large molecules or a large number of molecules, are instrumental to the development of next-generation technology for energy applications. In this project, we will develop a framework that efficiently translates quantum algorithms from a gate-based quantum computing model to one that can be efficiently run on a near-term quantum annealer to enable large-scale electronic structure theory simulations across different quantum computing architectures. These algorithms will offer an adaptive approach to predicting both the ground and excited electronic states of molecules, which has direct applications in simulating the photodynamics of macromolecules and materials related to but not limited to solar energy harvesting and conversions.

09/25/2023

Jared Auclair

Chemistry and Chemical Biology
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Sponsor: Amgen Foundation

Amgen Biotech Experience (ABE) Massachusetts

The ABE MA is a multiple year STEM grant to bring biotechnology to the high school classrooms throughout MA. It consists of professional development for teachers and deployment of curriculum into high school classrooms.

09/19/2023

Srirupa Chakraborty

Chemistry and Chemical Biology
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Sponsor: NIH

Modeling the mucosal glycopeptide mesh for improved disease understanding and mucin-inspired biomaterial design

Mucins and other densely glycosylated proteins play critical roles in a number of biological processes, disease conditions, and therapeutics. The functioning of these sugar-coated molecular machines depends on their structure, dynamics, and conformational transitions. Experimental techniques for capturing such structural dynamics, however, can be extremely challenging and resource intensive. We seek to improve upon some of the existing glycan modeling computational tools as well as design new in silico techniques, as robust alternatives to experimental studies. These tools will be used to build interconnected mucin glycoprotein gel systems with native glycosylation patterns, and obtain understanding of functional underpinnings at the molecular level.

09/19/2023

Cristina Schultz

Marine and Environmental Sciences
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Sponsor: NOAA

mCDR 2023: Developing a coupled benthic-pelagic biogeochemical model to evaluate the effectiveness of mCDR interventions

Deep cuts to emissions across all sectors are needed in order to limit global warming to 1.5˚C to 2˚C above preindustrial values. If zero emission is ever to be achieved, further implementation of carbon dioxide removal (CDR) strategies are also necessary to offset emissions from hard-to- abate sources. This project will focus on two CDR approaches with direct influence on the ocean sediment: seaweed farming and further sinking into the deep ocean and restoration of “blue carbon” coastal ecosystem, more specifically cessation of bottom trawling to preserve sediment carbon. We will do so by developing a new model for the ocean sediment and benthos that can be coupled to existing ocean models to simulate these strategies and quantify their effect on the carbon cycle as well as understand potential feedbacks that could impact the ocean ecosystem.

09/18/2023

Darien Wood

Physics
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Sponsor: NSF

Experimental Particle Physics Research at High Energies

This grant supports the work of three faculty members at Northeastern University (Barberis, Orimoto, and Wood) plus several postdoctoral researchers and students on the CMS experiment at the CERN Large Hadron Collider (LHC). The program includes analysis of CMS data in carefully chosen physics topics, including searches for leptoquarks and for the production of pairs of Higgs bosons, and measurements of standard model production of W+jets and ZZ pairs. It also includes support and development of the current detector for taking new data, and development of instrumentation upgrades that will enable CMS to exploit future high luminosity running of the LHC(HL-LHC). The group has leading roles in the operations and upgrades of the CMS Muon system, the muon trigger, the electromagnetic calorimeter, and the new MIP timing detector.

09/15/2023

Qimin Yan

Physics
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Sponsor: NSF

DMREF: Deep learning guided twistronics for self-assembled quantum optoelectronics

This grant is from the NSF Designing Materials to Revolutionize and Engineer our Future (DMREF) program and aims to accelerate the discovery and deployment of multi-layer twisted 2D systems for quantum optoelectronics.

09/08/2023

Aaron Seitz

Psychology
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Sponsor: NIH

Understanding Mediating and Moderating Factors that Determine Transfer of Working Memory Training

This proposal aims to improve the rigor and reproducibility of research on plasticity in human working memory (WM), and related executive functions (EFs) in adolescent youth. We address a critical gap between research and practice that is characterized by a growing commercial space marketing cognitive training approaches (with WM being one of the most common targets), which are particularly catering to typically developing children and those diagnosed with ADHD to improve mental health and scholastic performance. However, despite expansive literature, there exists limited basic research on WM and EF training in adolescents, and both methods and findings are mixed across studies. Here, we address these significant gaps that pose obstacles to understanding interventions’ reliability and validity by collecting a large-scale open dataset that compares different training approaches on a common set of outcome measures.

08/21/2023

Lori Ferrins

Chemistry and Chemical Biology
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Sponsor: ACS

ACS Medicinal Chemistry Predoctoral Fellowship

This fellowship funds a year of research in the field of medicinal chemistry through a sponsorship by Genentech.

08/16/2023

Max Bi

Physics
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Sponsor: NIH

Integrative biophysical modeling for collective tissue mechanics

Organ surfaces, made of epithelial or endothelial cells, serve as physical barriers. These cells are generally static but can transition to a dynamic, migratory state during physiological processes like development and repair. Traditional studies focus on these cells in 2D flat surfaces, which doesn't translate well to natural epithelia that often have curved geometries and varied topologies like spheres and tubes. Key questions remain about how curvature affects cell collective movement and the mechanics of multilayered tissues like mammalian epidermis. These issues are particularly critical during epidermal development, where cues and timescale-dependent mechanics are not well understood. To address these gaps, I plan to develop computational models that go beyond the conventional 2D approach, incorporating curved and multilayered 3D surfaces. This will include new models exploring the biomechanical relationship between nuclear shapes and cell proliferation.

08/08/2023

Alexandra Rodman

Psychology
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Sponsor: NIH

Behavioral and neurocognitive mechanisms linking peer victimization to adolescent psychopathology

Adolescence is a period of heightened vulnerability for many forms of psychopathology. This vulnerability comes at a time when emotional and physiological responses to peer rejection are elevated, rendering peer victimization particularly damaging. Despite the strong links between peer victimization and internalizing problems during adolescence, the behavioral and neural mechanisms underlying this association remain unclear. The proposed project will test a novel conceptual model, whereby two underlying dimensions of peer victimization, peer threat (e.g., presence of negative social experiences, like rejection) and peer deprivation (e.g., absence of positive social experiences, like ostracism) differentially shape neurocognitive processes and social behaviors that have relevance for psychopathology. We test this conceptual model using experimental and observational approaches in an intensive longitudinal design, including experimental and fMRI tasks, digital phenotyping, and predictive modeling approaches. This work is a necessary first step in developing targeted interventions to mitigate the effects of peer victimization during adolescence.

08/07/2023

Stephanie Noble

Psychology
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Sponsor: NIH

Empirical Power Analysis Tool for fMRI

Functional magnetic resonance imaging (fMRI) research has transformed our understanding of human brain function and disease, but recent work has exposed an endemic lack of statistical power (i.e., ability to detect effects of interest) and a need for power analysis tools that meet the demands of the typical user. We propose to create a web-based power calculator tailored to typical fMRI studies that only requires the user to specify information readily available to them. By enabling researchers to more easily and accurately plan studies for desired levels of power, this power calculator will promote more robust and reproducible findings in the field.

08/03/2023

Randall Hughes

Marine and Environmental Sciences
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Sponsor: Mass Dept of Fish & Game, Div Marine Fisheries

Seed collection and propagation of eelgrass (Zostera marina) for restoration efforts

This project funds a research assistant to collect and maintain a supply of eelgrass seeds that can be used in restoration efforts. They will also help MA DMF develop best practices for seed collection, storage, and distribution in support of state-wide restoration projects.

08/03/2023

Needa Brown

Physics
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Sponsor: DFCI

STING agonist drug delivery formulations synergize with PARPi to treat resistant, metastatic advanced breast cancer

The objective of this work is to generate clinically relevant data to support the use of PARPi in combination with local and systemic drug delivery platforms of STING agonists in order to treat metastatic, resistant breast cancer.

08/03/2023

Philip Deming

Psychology
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Sponsor: NIH

Probing negative affect circuits in humans using 7T fMRI

Negative mood is a common feature of anxiety, depression, bipolar disorder, and schizophrenia, which inflict immeasurable human suffering along with a combined economic burden of $600 billion in the US each year. The proposed research promises to deliver a new paradigm for studying the brain basis of negative affect, with the ultimate goal of developing targeted treatments for negative mood, a hallmark feature of many mental illnesses.

08/03/2023

Katie Lotterhos

Marine and Environmental Sciences
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Sponsor: U Gothenburg

A seascape of adaptations - Testing models that predict performance in multivariate environments

We are studying the adaptation of eelgrass to future ocean conditions in the Baltic Sea.

08/03/2023

Sijia Dong

Chemistry and Chemical Biology
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Sponsor: NSF

Collaborative Research: Enzyme-Mimicking Catalysts for Cellulose Processing

Lignocellulosic biomass from plants is a renewable, carbon-neutral material produced at a scale of 170-200 billion tons per year. The depolymerization of cellulose is a key step in biomass conversion, but it is challenged by the stability and crystalline nature of the cellulose fibers. We will develop synthetic catalysts based on molecularly imprinted nanoparticles that mimic endocellulase, exocellulase, and beta-glucosidase for the efficient hydrolysis of cellulose.

08/03/2023

Bryan Spring

Physics
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Sponsor: NIH

Fractionated photoimmunotherapy to harness low-dose immunostimulation in ovarian cancer

The Spring research group, in collaboration with the Enderling lab at Moffit Cancer Center, has been awarded a Physical Sciences Oncology Network grant (NCI U01 CA280849; ~$2.7M) titled "Fractionated photoimmunotherapy to harness low-dose immunostimulation in ovarian cancer". The project will harness an integrated experimental—mathematical oncology approach to decipher how to best harness immune sparing and immune stimulation of fractionated photoimmunotherapy to personalize treatments for advanced or recurrent ovarian cancer patients with presently dismal survival rates.

08/03/2023

Herbert Levine

Physics
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Sponsor: NSF

DMS/NIGMS 2: Regulation of Cellular Stemness during the Epithelial-Mesenchymal Transition (EMT)

We propose a joint theoretical/experimental research program to address cell-fate trajectories that occur during induction of EMT, the epithelial-mesenchymal transition. Specifically. recent efforts have indicated that epithelial cells can either undergo direct reprogramming to mesenchymal states or alternatively become more stem-like and exhibit hybrid E/M properties. Based on our preliminary investigations, we will use state-of-the-art single cell measurement technology together with advanced mathematical modelling frameworks to understand how cells choose specific fates and to quantitatively unravel the genetic and epigenetic dynamics that leads these cells along their particular trajectories. We will develop new mathematical concepts such as the role of frustration in cell fate networks, the effects of global competition on epigenetic interactions, the role of confluency in governing cell-cell interactions, and the introduction of model-based ideas into trajectory inference, as part of our investigation.

08/01/2023

Susanne Jaeggi & Aaron Seitz

Psychology
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Sponsor: Department of Defense (DoD), Office of Naval Research (ONR), Multidisciplinary University Initiative (MURI) #WU-24-0185 (NU sub: ST00019438)

A Computational Cognitive Neuroscience Framework for Attentional Control Traits and States

In this collaborative project that involves groups from Washington University (St. Louis), Brown University, University of California, Irvine, as well as several groups in Australia, we develop tools / apps to assess attention control in high-performing adults (e.g. pilots or air-traffic controllers) using computational modeling as well as behavioral and neuroimaging methods. Furthermore, we build evidence-based interventions to maximize and improve attention control functions in various environments (e.g. stressful environments, those that require long and sustained attention, etc.). The outcome of our project will provide a better understanding of the human attention system, and the interventions will enable individuals to maintain high levels of focus and concentration even in high-pressure situations, such as those faced by military personnel. This grant / project would be an excellent showcase to highlight our new center, the Brain Game Center for Mental Fitness and Well-Being, and thus, we'd love to be contacted with the COS Marketing and Communications team to talk about our ongoing and future work!

07/28/2023

Valerio Toledano Laredo

Mathematics
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Sponsor: NSF

Transcendental fiber functors, shift of argument algebras and Riemann-Hilbert correspondence for q-difference equations

This project stems from the recent discovery that quantum groups naturally arise from the Stokes data of differential equations associated to classical symmetries. The main goals are to further explore this bridge between classical and quantum symmetries. Of particular interest is the extension to difference equations, which are natural discretisations of differential equations, and whose Stokes data are not well-understood beyond the one-variable case. Another important direction will the study of the integrable systems, or constants of motion, corresponding to these differential and difference equations. The project will provide research training opportunities for graduate students.

07/28/2023

Xuwen Zhu

Mathematics
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Sponsor: NSF

Microlocal analysis and singularities

Degenerations and singularity formations play important roles in the study of differential geometry and arise naturally in multiple other areas of mathematics, including, algebraic geometry, mathematical physics, number theory, and representation theory. This project concerns the geometry of singularities and has interesting connections with an array of disciplines including modeling of electromagnetic systems, gauge theory and string theory. Building on her track record, the PI plans to use effective techniques to solve a wide variety of problems and discover new and sharper analytic results. Alongside her research, the PI will engage in various outreach activities, with a focus on fostering mentoring networks for undergraduate and graduate students.

07/20/2023

Roman Manetsch

Chemistry and Chemical Biology
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Sponsor: NIH

Activation of Benzoxaborole Prodrug AN15368, a Clinical Candidate for Chagas Disease

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is endemic in the Americas, but has also globalized due to human migration. Despite being one of the major causes of infection-induced heart disease worldwide, current therapies for Chagas disease have inconsistent efficacy and frequent side effects. A major contributor to treatment failure is thought to be the transiently dormant intracellular forms of T. cruzi that are resistant to otherwise highly effective trypanocidal compounds. The newly discovered benzoxaborole AN15368 represents the first extensively validated and safe clinical candidate for the treatment of Chagas disease. AN15368 acts as a prodrug that requires cleavage by parasite serine carboxypeptidases (TcCBPs) to yield the active metabolite. This proposal aims to gain additional understanding of this processing step for AN15368 as a prodrug, as well as to assess the potential for acquired resistance as this compound proceeds toward human clinical trials.

07/20/2023

Meni Wanunu

Physics
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Sponsor: NIH

Unidirectional single-file transport of full-length proteins through a nanopore

In this multi-PI project between the Wanunu Lab (Northeastern), Chen Lab (UMass Amherst), Aksimentiev Lab (Urbana Champaign), and Niederweis Lab (U Alabama), we will develop a next-generation single-molecule protein sequencer based on engineered high-resolution nanopores. Key reference to cite: Yu et al., Unidirectional single-file transport of full-length proteins through a nanopore, Nature Biotechnology, 2023. DOI: https://doi.org/10.1038/s41587-022-01598-3

07/20/2023

Qimin Yan

Physics
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Sponsor: DOE

Synthesis of motif and symmetry for accelerated learning, discovery, and design of electronic structures for energy conversion applications

The goal of the proposed work is to develop the data-driven approach based on structure motifs and orbital symmetries to discovery and design inorganic semiconductor compounds with optimal electronic structures for energy conversion applications. Objectives are: (i) to develop a framework toward the universal description of structure motifs as well as crystal/orbital symmetries in inorganic compounds; (ii) to accelerate the motif and symmetry based discovery and design of oxide and layered semiconductor compounds with optimal electronic properties for energy conversion applications; iii) to enable the effective learning of structure motifs and orbital symmetries through the combined use of national language processing, graph theory, and deep learning.

07/19/2023

Iva Halacheva

Mathematics
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Sponsor: NSF

Categorical centers, cactus actions, and diagram algebras

This project delves into several research directions within representation theory, which is the mathematical framework for studying objects through their symmetries and the operations which preserve them. Such operations can carry a classical, or even more intriguingly a quantum algebraic structure. Originally appearing in physical models within statistical mechanics and quantum integrable systems, quantum groups and the theory surrounding them are now a thriving source of uncovering new mathematical principles. This project will develop a richer understanding of this theory by building a common ground for combining algebraic, combinatorial, and higher-structural categorical techniques for the study of quantum groups and associated diagram algebras. This will lead to a more unified approach and provide connections between several areas of mathematics, as well as potential physical applications. The project will involve the participation of undergraduate students and create opportunities for discussion and collaboration among early-career researchers.

06/08/2023

Randall Hughes

Marine and Environmental Sciences
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Sponsor: Ramboll US Consulting

Genetic assessment and native plant production for the US Army Corps of Engineers BAA 6 Belle Isle Project, Boston, MA

Genetic variation can be critical for population performance and resilience, yet it is seldom accounted for in habitat restoration efforts. This project will assess the genetic diversity of the dominant salt marsh plants Spartina alterniflora and Spartina patens in natural marshes in and around Belle Isle Marsh, MA. We will also produce local stocks of each of these species from seed and compare their genetic and phenotypic diversity in a common greenhouse environment. This work will inform ongoing and future marsh restoration efforts in Belle Isle and the surrounding region.

06/07/2023

Mauricio Santillana

Physics
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Sponsor: NIH

Development of an Open-Source and Data-Driven Modeling Platform to Monitor and Forecast Disease Activity

The objective of this grant is to leverage a wealth of information from a diverse array of data sources to build a modeling platform capable of combining information to produce real-time estimates and forecasts of disease activity (Dengue and Influenza) at multiple geographic scales--nation, state, and city--using Brazil as a test case. Additionally, we will use machine learning and mechanistic models to understand disease dynamics at multiple spatial scales, across a heterogeneous country such as Brazil.
06/07/2023

David Kimbro

Marine and Environmental Sciences
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Sponsor: NSF

The influence of biophysical coupling and cross-scale interactions on ecosystems of the Plum Island LTER

Understanding salt marsh ecosystems is crucial because marsh plants create unique and productive wetland habitat in temperate estuaries for a variety of economically valuable and ecologically important fishes, birds, and invertebrates. In addition to creating habitat, salt marshes provide key ecosystem services by removing excess nutrients from terrestrial run-off, buffering shorelines from storm erosion, and sequestering atmospheric carbon. In the Merrimack River-Plum Island estuarine system just north of Boston, some salt marshes can receive copious amounts of allochthonous inputs in the form of marsh plant detritus (i.e., large mats of “wrack”), while other salt marshes do not. This project will use aerial imagery, drones, and AI to quantify whether wrack accumulates into hierarchically organized hot spots according to predictions based on the oceanography of the system. Outdoor field and laboratory experiments will then be conducted to determine whether the oceanographically-generated landscape patterns of wrack set the pace for food web dynamics in this critical ecosystem. This project is funded by the National Science Foundation.
06/07/2023

Eddie Geisinger

Biology
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Sponsor: Broad Inst

Attacking failure of antibiotic treatment by targeting antimicrobial resistance enabler cell-states

This project aims to uncover the genetic mechanisms that underlie antibiotic treatment failure in hospital-acquired bacterial infections. We will analyze "enabler" mutations and phenotypes that promote antibiotic tolerance and act as stepping stones for the development of antibiotic resistance and treatment failure. A major focus is the pathogen Acinetobacter baumannii, which causes hospital-acquired diseases including pneumonia and sepsis that have become increasingly difficult to treat.
06/07/2023

Jon Tilly

Biology
|
Sponsor: NSF

Role of Mitochondria as Intracellular Shuttles for Nuclear Gene-regulatory Transcription Factors During Pluripotent Cell Division and Fate Specification

This project combines our technological advancements in mitochondrial analysis and nanosorting with an in-vivo mitochondrial lineage tracing approach, which will enable us able to map the developmental fate of specific mitochondrial subtypes in mammalian eggs through post-fertilization to the point in early embryogenesis when the inner cell mass and trophectoderm are specified at the first cell-fate decision. This project will also explore the novel concept that subtypes of mitochondria, which differ in their biochemical properties, proteomic landscapes, and segregation patterns during asymmetric cell divisions, serve as transcription factor shuttles that then guide stem cell fate decisions and lineage commitment during development
06/01/2023

Needa Brown

Physics
|
Sponsor: DOD/USAMRAA

Combination Intraperitoneal Local Delivery of PARPi Implants and Anti-PDL1

Aggressive metastatic ovarian cancer patients have limited therapy options and clinical trials to evaluate promising alternative combinations have been limited due to the high toxicity. Here we propose a bio/nanoformulation approach to delivery PARPi directly into the peritoneal cavity for sustained release and limited toxicity in combination with innate and adaptive immune modulating nanoparticles of ADU-S100 and anti-PDL1.
06/01/2023

Paul Champion

Physics
|
Sponsor: NSF

Collaborative Research: Mapping and comparing the link of the protein scaffold to quantum events in thermally activated enzymes and flavin‐based photoreceptors.

This work will enhance understanding of how biology integrates quantum behavior into macromolecular function. Proteins and macromolecules have evolved to rely, at least to some degree, on underlying quantum phenomena such as tunneling and spin coherence. The biological outcomes depend on the interplay between the scaffold of the protein (which is often treated classically) and the quantum behavior found within more localized regions of the protein. Investigators within this collaboration will draw upon both experimental and theoretical efforts that focus on hydrogen tunneling and vibrational energy transport in lipoxygenase catalysis as well as on optically excited radical pair formation, spin coherence, and decay in proteins (cryptochromes) that are associated with magnetoreception and circadian clocks.
06/01/2023

Neel Joshi

Chemistry
|
Sponsor: Novo Nordisk Foundation

Soft wearables with high energy density: merging chemical biology and silicone chemistry with compliant active devices (WeArAble)

The purpose of this grant is to develop soft, wearable actuators with enhanced power output compared to the state of the art by combining cutting edge synthetic and biosynthetic materials. Existing wearable actuators either require bulky power sources and rigid "exoskeletons" to be effective, or are limited in their utility by low power outputs. The grant represents a collaboration between Northeastern, Technical University of Denmark, and EPFL (Switzerland). The Joshi lab at Northeastern will focus on developing protein fiber materials from engineered bacteria with optimal mechanical and electrostatic performance.
06/01/2023

Albert-László Barabási

Physics
|
Sponsor: Templeton Fndn

Using Big Data to Quantify and Cultivate Genius

We aim to identify early career markers that suggest that an individual has the potential to achieve exceptional performance and possibly, professional and public recognition. We aim to determine the earliest point in a career when these achievements can be detected and predicted, quantify the delay between performing groundbreaking work and receiving academic and public recognition, and ultimately develop a quantitative prediction model to explore the possibility of nurturing future exceptional performance in science.
04/05/2023

Sue Whitfield-Gabrieli

Psychology
|
Sponsor: NIH

Targeting adolescent depression symptoms using network-based real-time fMRI neurofeedback and mindfulness meditation

Adolescents experience alarmingly high rates of major depressive disorder (MDD), and these episodes are highly recurrent and increase suicide risk. Recently, the U.S. Surgeon General and leading pediatric health organizations declared a national state of emergency for adolescent mental health, underscoring that the majority of affected adolescents do not receive adequate treatment. As gold-standard depression treatments (antidepressant medications and cognitive behavioral therapy) are effective for only ~50% of adolescents, there is a critical need to develop novel treatments to improve clinical outcomes, particularly those that target core mechanisms fundamental to MDD.  Rumination (i.e., repetitive, negative patterns of thinking typically focused on the self) contributes to MDD onset, maintenance, and recurrence as well as predicts treatment non-response and relapse. Mindfulness meditation has been shown to suppress the default mode network (DMN), a set of brain regions that are overactive in depression and that underlie rumination.   We are launching a large scale, clinical trial to do a mindfulness based real-time fMRI neurofeedback intervention in adolescents with MDD in order to quiet the DMN and mitigate rumination.

04/04/2023

Rhea Eskew

Psychology
|
Sponsor: NSF

Time-locked psychophysics: speeded responses to visual stimuli

The project will use variations on a classic method called response time (RT) measurement, which has human participants respond as quickly as possible to the presentation of carefully-controlled visual patterns.  One goal is to demonstrate that the fastest RTs are triggered by the very early responses in the photoreceptors of the retina of the eye. Two parallel pathways in the visual system called ON and OFF pathways, generate opposite-polarity responses. A second goal is to test the hypothesis that these two pathways can be measured and studied separately using these speeded behavioral responses

04/03/2023

Sam Munoz

Marine and Environmental Sciences
|
Sponsor: NSF

CAREER: Sedimentary signatures of large riverine floods to constrain risk and build resiliency

The traditional paradigm in river and floodplain management relies almost exclusively on stream gage measurements as the key dataset informing flood hazard assessments, while largely neglecting the geomorphic dynamics and resulting sedimentary records preserved in floodplains. This project builds on prior work in the development and application of stratigraphic records in floodplains by harnessing recent advances in hydraulic modeling, environmental sensors, and sedimentology to constrain flood hazard assessments. This research is integrated with an education and outreach plan designed to attract, motivate, and train community college students in geoscience research through an established internship program.

03/08/2023

Loretta Fernandez

Marine and Environmental Sciences, Civil and Environmental Engineering
|
Sponsor: NOAA

Determining how aquaculture grow-out methods can reduce the negative effects of parasites and micropollutants on farmed oysters  

We will be collaborating with local oyster farmers to investigate how growing methods (on the bottom vs. Floating) and water quality affect the prevalence and intensity of common oyster parasites. The knowledge developed through this work will be shared with various stakeholders through workshops and aquaculture professional associations.  

03/03/2023

Sijia Dong and Hannah Sayre

Chemistry and Chemical Biology
|
Sponsor: DOE

Bioinspired Light-Escalated Chemistry (BioLEC) 

The mission of the BioLEC Energy Frontier Research Center (EFRC) is to combine light harvesting and advances in solar photochemistry to enable more powerful editing, building, and transforming of abundant materials to produce energy-rich feedstock chemicals. As part of the BioLEC EFRC, we will develop new supercharged light-powered catalysts and reactions an deepen our understanding of existing ones, through which valuable products can be generated from plentiful molecules such as those extracted from waste and renewal resources.  

03/03/2023

Bryan Spring

Physics
|
Sponsor: NIH

Disease-homing light delivery by engineering bioluminescent immune cells for whole body precision photomedicine 

Photomedicine avoids traditional side effects of systemic chemotherapy, yet effective outcomes are dependent on direct irradiation from an external light source that limits the scope and the types of cancers that may be treated. This proposal develops a precision photomedicine platform that exploits natural disease-homing properties of the immune system to mediate bioluminescence-activated phototherapy in combination with established technology to deliver photoactive therapeutic agents selectively to tumor cells. Successful, proof-of-concept studies will establish a new paradigm of systemic, whole-body phototherapy by enabling immune cell-based light delivery to deep and diffuse metastatic disease that would otherwise be impractical to treat using an external light source, thereby overcoming a major limitation of conventional phototherapy. Photomedicine avoids traditional side effects of systemic chemotherapy, yet effective outcomes are dependent on direct irradiation from an external light source that limits the scope and the types of cancers that may be treated. The proposal develops a precision photomedicine platform that exploits natural disease-homing properties of the immune system to mediate bioluminescence-activated phototherapy in combination with established technology to deliver photoactive therapeutic agents selectively to tumor cells. Successful, proof-of-concept studies will establish a new paradigm of systemic, whole-body phototherapy by enabling immune cell-based light delivery to deep and diffuse metastatic disease that would otherwise be impractical to treat using an external light source, thereby overcoming a major limitation of conventional phototherapy.  

This high-risk, high-reward concept grant will be performed by the Spring Lab at Northeastern University in collaboration with the Schaffer-Nishimura Lab at Cornell University. 

03/03/2023

Eddie Geisinger

Biology
|
Sponsor: NIH

Repurposing Gram-positive Antibiotics for Gram-Negative Bacteria using Antibiotic Adjuvants 

The multidrug-resistant (MDR) sepsis pathogen Acinetobacter baumanni presents an enormous ongoing challenge to public health. Current treatment options for infections with these bacteria are extremely limited. Our research examines a class of small molecules called antibiotic adjuvants that greatly boost the activity of several existing antibiotics against A. baumanniim, with the goal of developing new combination approaches to treat MDR infections.  

01/26/2023

Carolyn Lee-Parsons

Chemistry and Chemical Biology, Chemical Engineering
|
Sponsor: NSF

PlantSynBio: A Novel CRISPR SynBio Tool for Investigating and Reprogramming the Regulation of Alkaloid Biosynthesis in Catharanthus roseus 

Plants produce a white array of valuable, biologically active natural products we use as medicines. This grant will enable engineering for enhanced drug production from the medical plant, C. roseus.

01/20/2023

Rebecca Sherbo

Chemistry and Chemical Biology
|
Sponsor: Catalyst Grant, Schmidt Science Fellows

Identifying factors that promote soft coral resilience in climate change-induced

This work, in collaboration with a biophysicist, will explore the resilience of soft corals to rising ocean temperatures by understanding two main adaptations: the coral microbiota, and the morphology and growth patterns.

01/18/2023

Rebecca Shansky

Psychology
|
Sponsor: NIH

Sex-dependent pain processing circuitry in classical Pavlovian fear conditioning

Traumatic experiences create powerful memories by linking information about the trauma itself with environmental cues associated with the event. Our lab has found evidence that males and females may form these memories using different brain regions, and this grant will allow us to probe this question more deeply by recording neural activity in real time as animals are learning.

01/11/2023

Justin Reis

Marine and Environmental Sciences
|
Sponsor: NOAA

Polymorph mineralogy & fraction of calcium carbonate (CaCO3) sediments across the western North Atlantic shelf (Gulf of Maine to Chesapeake Bay)

Prof. Justin Ries was funded to collect and analyze sediments from the western Atlantic shelf (Maine to Maryland) as part NOAA's third East Coast Ocean Acidification (ECOA-3) cruise aboard the NOAAS Ronald H. Brown -- NOAA's only scientific ship for global scale oceanographic survey. The objective of Prof. Ries' specific project is to characterize the distribution and composition of calcium carbonate sediments deposited within shelf sediments of the western Atlantic shelf. Characterizing the distribution and composition of shelf carbonates will improve our understanding of future CO2-induced climate and ocean change because these alkaline minerals have the capacity to moderate the effects of rising atmospheric CO2 as they dissolve in the ocean in response to CO2-induced acidification. Prof. Ries is working on this project as part of a large, interdisciplinary and collaborative team of marine ecologists, geochemists, microbiologists, and sedimentologists.
11/21/2022

Laurel Gabard-Durnam

Psychology
|
Sponsor: Gates Foundation

The goals of this award are first to design and validate a scalable, affordable hardware-software package that reliably measures brain function via EEG in babies over the first two years of life. Second, in multi-country studies using this EEG system, we will establish which measures of early brain function track healthy developmental changes associated with early cognitive and language development across contexts and are sensitive to pre- and postnatal risk factors for brain development. Finally, we will establish which EEG measures of brain function are robust enough to serve as biomarkers to evaluate clinical intervention trial efficacy in early life.

11/02/2022

Sam Munoz

MES
|
Sponsor: US Geo

Riverine flooding is a perennial hazard in the heavily populated Northeastern United States, and improving near- and long-term forecasts of flooding in this region is of critical importance for regional water resource management, infrastructure planning, and fisheries. In this project, we will harness advances in climate reanalysis and modeling to (i) identify the ocean-atmosphere patterns that generate flooding in New England and (ii) evaluate the contribution of greenhouse forcing on flood-generating mechanisms in this region.

10/05/2022

Gabor Lippner

Math
|
Sponsor: Simons Foundation

Graph theory - the mathematical study of networks has originally developed as a part of discrete mathematics and combinatorics. This has changed significantly in the past 20 years following discoveries of connections to Linear Algebra and later to Geometry and even to Real Analysis. The goal of this project is to find new applications to, as well as expand the scope of, these connections.

10/05/2022

Michele Di Pierro

Physics
|
Sponsor: NIH

The aim of the project is to gain mechanistic understanding of the relationships among non-coding genomic variation, phenotype, and disease. To achieve this aim, researchers will combine data from DNA-DNA proximity ligation assays and multiple genome alignments to extract coevolutionary information about DNA elements and to infer the network of functional interactions among them.

08/23/2022

Fabian Ruehle

Physics
|
Sponsor: NSF

String theory has evolved into one of the most complex theories devised by mankind to date. Its goal is to describe our Universe from the smallest to the largest scales. In my research proposal, I suggest to use latest advances in mathematics and artificial intelligence to uncover answers to fundamental questions hidden within this theory.

08/18/2022

Pran Nath

Physics
|
Sponsor: NSF

This research will investigate the laws of physics at short length and time scales not yet understood using symmetry principles and mathematical and machine learning tools. Analyses of data expected from the Large Hadron Collider, in Geneva, Switzerland to detect possible evidence of strings and new physics will be undertaken.

08/17/2022

Clemens Bauer Hoss

Psych
|
Sponsor: NIH

Auditory hallucinations are one of the five cardinal symptoms of schizophrenia and one of the most distressing. Almost a third of patients experiencing auditory hallucinations are not responsive to gold-standard pharmacological and psychotherapeutic treatment. We have pioneered a new non-invasive treatment candidate, computational neuroscience-based approach, also known as network-based real-time functional Magnetic Resonance Imaging (fMRI) Neurofeedback that is a well-tolerated and effective approach for reducing the severity and frequency of auditory hallucinations. However, because this technique currently requires fMRI to deliver neurofeedback, which unfortunately is an expensive procedure involving a complex setup and participant burden, this NIH award will help develop novel, non-invasive, personalized, and scalable treatments that will improve outcomes and reduce relapse rates among schizophrenia patients with treatment resistant auditory hallucinations.

08/02/2022

Jennifer Bowen

MES
|
Sponsor: NSF

Salt marshes provide an important line of defense against nutrient pollution by intercepting watershed nitrogen before it enters estuaries. This nitrogen can enhance the growth of marsh plants, however some forms of nitrogen can also be used by microbes, who use it to decompose organic matter in low-oxygen sediments. Understanding which of these two outcomes is most likely to occur is important because, if marsh plants take up that nitrogen and grow more robustly, this will increase salt marsh resilience to sea-level rise. On the other hand, if microbes use that nitrogen for respiration, it could accelerate loss of organic matter, thereby decreasing resilience. This project combines field and greenhouse experiments to tease apart the relative importance of different N forms on the plant and microbial communities that ultimately dictate salt marsh resilience.

07/27/2022

Max Bi

Physics
|
Sponsor: HFSP

To answer this question, Dapeng “Max” Bi (COS-Physics) has been awarded a collaborative HFSP grant with Friedhelm Serwane (LMU Munich, Germany) and Tamal Das (Tata Institute for Fundamental Research Hyderabad, India). Together, the team will develop a biomechanical understanding of the epidermis, which is critical for preventing and curing numerous skin defects, painful blistering, and skin cancers.

The International Human Frontier Science Program (HFSP) organization supports novel, innovative and interdisciplinary basic research focused on the complex mechanisms of living organisms. The award is highly competitive, and this year only four percent of the applicants were selected for funding.

07/26/2022

Sara Constantino

Psychology
|
Sponsor: NSF

Addressing collective action problems such as climate change requires individuals to engage in a host of coordinated behaviors to effect widespread systemic changes. Yet, while most people are concerned about climate change, they systematically underestimate others’ concern, which can inhibit action toward addressing collective challenges. Drawing on interdisciplinary research, this project uses mixed methods to develop and test an integrative framework illuminating drivers of pervasive social misperceptions and pathways for correcting these biases.

07/24/2022

Albert-László Barabási

Netsci
|
Sponsor: NSF

Healthy debate is a cornerstone of scientific progress, but no one really knows when, how, and why these debates in science happen. In our funded research, we will use new computational techniques to automatically identify debates across the entire published scientific literature. We will study these debates to understand the role of disagreement in science and find policies that harness the power of debate to increase the pace of scientific discovery.

07/22/2022

Sam Munoz

MES
|
Sponsor: NSF

The degradation and transport of plastics has led to its accumulation across a range of environments, but a key component of the plastic-carbon cycle — namely the transport and storage of microplastics through rivers and floodplains — remains poorly constrained. Understanding where and why plastics accumulate along rivers and floodplains is critical for mitigating and managing plastic pollution because rivers connect plastics production and use upstream to coasts and the open ocean. This project will analyze soil samples to quantify the amount and types microplastics found in different floodplain environments, and relate patterns of plastic accumulation to environmental parameters.

07/21/2022

Aron Stubbins

MES
|
Sponsor: Running Tide

To slow climate change we need to stop burning fossil fuels and to find ways to capture carbon dioxide from the atmosphere. When kelp and other macroalgae grow, they store carbon in their biomass, but they also continuously release organic carbon into ocean waters. The current project aims to understand whether this released organic carbon is also stored, not in the seaweeds themselves, but in the deep sea. Understanding what happens to all the carbon seaweeds capture is critical to Running Tide technologies that seek to use macroalgae to remove sufficient carbon dioxide from the atmosphere to help slow or reduce climate change.

07/21/2022

David DeSteno

Psychology
|
Sponsor: Templeton

The John Templeton Foundation has awarded a $1 million grant to Professor David DeSteno to support his PRX Podcast “How God Works.” The podcast, which brings a scientific eye to examining how and why spiritual practices foster human flourishing, has appeared on Apple’s Top Ten List for science podcasts, and was recognized with honoree status by the Webby Awards in the Science Education category during its first year. The new grant will fund it for 4 more  8-episode seasons and provide funds for several live events to be held in cities across the US.

07/15/2022

Mary Jo Ondrechen

CCB
|
Sponsor: NSF

This project’s overall goal is to build a knowledge base that will enable the design of enzymes that can catalyze industrial chemical reactions with less energy consumption and fewer unwanted by-products than many of the current conventional processes. Several dozen students, in both the research laboratories and the classroom, will be trained in computational and experimental techniques.

06/15/2022

Dacheng Lin

Physics
|
Sponsor: STSI
06/07/2022

Mark Williams

Physics
|
Sponsor: NIH

HIV-1 integrates its genome into infected host cells. Due to the permanence of the integrated genome, it is advantageous to target HIV-1 replication in early stages, before integration. To rationally design new inhibitors of these early replication steps, a detailed molecular understanding is required. This work proposes integrated biochemical, biophysical, and cellular approaches to probe critical steps in early viral replication.

05/27/2022

Milen Yakimov

Mathematics
|
Sponsor: NSF

Noncommutative Algebras and Monoidal Triangulated Categories

05/27/2022

Jason Guo

Chemistry and Chemical Biology
|
Sponsor: NIH

This award is to acquire a 600MHz NMR spectrometer primarily for medicinal chemistry applications

03/26/2022

Steven Lopez

Chemistry
|
Sponsor: NSF

NSF Early Investigator (CAREER) Workshop Award

03/25/2022

Alain Karma

Physics
|
Sponsor: NASA

Using Space to Improve Solidification Processes on Earth

03/25/2022

Charles Hillman

Psychology
|
Sponsor: University of Illinois

Enhancing Children’s Cognitive Function and Achievement through Carotenoid Consumption

03/01/2022

Reese Bauer

Linguistics
|
  This money will go towards funding studies that look to improve jury instructions and aim to reform the justice system in the United States.
02/24/2022

Sanjeev Mukerjee

Chemistry
|
Sponsor: DOE/Giner

Liquid Electrolytes for Lithium-Sulfur Batteries with Enhanced Cycle Life and Energy Density Performance.

02/24/2022

Dagmar Sternad

Biology
|
Sponsor: NIH

Predictability in complex object control.

02/24/2022

Pete Bex

Psychology
|
Sponsor: NIH

Assessment and Rehabilitation of Binocular Sensorimotor Disorders.

02/04/2022

Samuel Munoz, in collaboration with Sylvia Dee and James Doss-Gollin at Rice

Marine and Environmental Sciences
|
Sponsor: NSF

Collaborative Research: Evaluating the Past and Future of Mississippi River Hydroclimatology to Constrain Risk via Integrated Climate Modeling, Observations, and Reconstructions

02/04/2022

Meni Manunu

Physics
|
Sponsor: PFI-TT NSF

Developing an integrated platform for high accuracy measurements of viral particle count and infectious titer.

01/28/2022

Jonathan Khan

Biology and Law
|
Sponsor: National Library of Medicine

The Uses of Diversity: Managing Race and Representation in Law, Politics, and the Biosciences.

01/28/2022

Leila Deravi

Chemistry
|
Sponsor: ONR

A Portable, Bio-inspired Platform for Photo-Responsive Sensing and Display

01/07/2022

Steven Lopez

Chemistry
|
Sponsor: NSF

CAREER: Multiscale photodynamics simulations in solvated and crystalline environments

01/07/2022

Tovah Day

Biology
|
Sponsor: NSF

CAREER: Mechanisms of G4 DNA induced genome instability

12/16/2021

Tsuguo Aramaki

Physics
|
Sponsor: NASA

The GAPS Experiment: A Search for Dark Matter Using Low-Energy Antiparticles

 

10/18/2021

Laurel Gabard-Durnam

Psychology
|
Sponsor: Wellcome Leap

KHULA LEAP: a multiscale approach to characterizing developing executive functions

10/18/2021

Steven Lopez

Chemistry and Chemical Biology
|
Sponsor: NSF

Institute for Data Driven Dynamical Design

10/18/2021

Gregory Fiete

Physics
|
Sponsor: DOE

Designing Strong stability in non-critical and rare-earth-lean-magnetic materials

10/18/2021

Bryan Spring

Physics
|
Sponsor: RSCA, CZI, FGCF

Movement as a vital sign in preterm infants

10/05/2021

Heather Brenhouse

Psychology
|
Sponsor: NIH

Mechanisms driving development of threat sensitivity following early life adversity

09/07/2021

Gregory Fiete

Physics
|
Sponsor: NSF

Nonequilibrium Control of Magnetism and Topology Through Selective Phonon Excitation

09/06/2021

Bryan Spring

Physics
|
Sponsor:  the Chan Zuckerberg Initiative (CZI)

Ten multidisciplinary research teams will receive a combined $1,150,000 in funding as part of the inaugural year of Scialog: Advancing BioImaging, a three-year initiative, supported by Research Corporation for Science Advancement (RCSA), the Chan Zuckerberg Initiative (CZI) and the Frederick Gardner Cottrell Foundation (FGCF), that aims to accelerate the development of the next generation of imaging technologies. Bryan Spring, Physics, Northeastern University, has teamed up with Barbara Smith, Biological and Health Systems Engineering, Arizona State University to develop a unique combination of fiber-optic photoacoustic and multiphoton microscopy in a miniaturized device that facilitates comprehensive, high-resolution volumetric renders of the fallopian tube to precisely locate and to ablate premalignant tumors.

09/06/2021

David DeSteno and Lisa Feldman-Barrett

Psychology
|
Sponsor: The John Templeton Foundation

Academic Ideas in the Public Sphere: Teaching Scientists and Philosophers How to Communicate with the Public

09/06/2021

Heather Brenhouse

Psychology
|
Sponsor: NIH

Mechanisms driving the development of threat sensitivity following early life adversity

09/06/2021

Dagmar Sternad

Biology
|
Sponsor: NSF

Movement as a Vital Sign in Preterm Infants

09/06/2021

Steven Lopez

Chemistry & Chemical Biology
|
Sponsor: NSF

Harnessing the Data Revolution program

09/06/2021

Aron Stubbins

Marine and Environmental Sciences
|
Sponsor: NSF Office of Ocean Sciences

EAGER: Collaborative Research: Assessing the contribution of plastics to marine particulate organic carbon

09/06/2021

George O’Doherty

Chemistry
|
Sponsor: NSF

De Novo Asymmetric Synthesis of Natural and Unnatural Oligosaccharide Motifs

09/06/2021

Carla Mattos

Chemistry
|
Sponsor: NSF

Allosteric effects in the complexes between Ras proteins and Raf

09/06/2021

Andrew Feiguin

Physics
|
Sponsor: NSF

The many-body problem in the age of quantum machine learning

09/06/2021

Eddie Geisinger

Biology
|
Sponsor: NIH/NIAID

Global Circuitry that Conotrols Acinetobacter Resistance and Virulence

05/17/2021

Sanjeev Mukerjee

Chemistry
|
Sponsor: Advent Technology Holdings

Noble Metal Free Low Temperature Electrolyzer for Hydrogen Generation

05/17/2021

Sanjeev Mukerjee

Chemistry
|
Sponsor: Department of Energy-Office of Energy Efficiency and Renewable Energy (EERE) (DE-FOA-0002044)

Durable MEA’s for Heavy Duty Fuel Cell Electric Trucks

05/17/2021

Sam Scarpino

Marine and Environmental Science
|
Sponsor: Tides Foundation and Rockefeller Foundation

COVID-19 Global health

04/12/2021

Carolyn Lee Parsons and Erin Cram

Biology
|
Sponsor: NSF

A Novel CRISPR SynBio Tool for Investigating and Reprogramming the Regulation of Alkaloid Biosynthesis in Catharanthus roseus

04/12/2021

Randall Erb and Alain Karma

Physics
|
Sponsor: NASA

Structure property processing correlations in freeze-cast biomimetic materials

01/11/2021

Dagmar Sternad

Biology
|
Sponsor: NSF

Emergent motor timing influences perpetual timing

01/11/2021

Kim Lewis

Biology
|
Sponsor: NIH

Evaluating darobactins as antimicrobial agents

01/08/2021

Mike Pollastri

Chemistry
|
Sponsor: NIH/NIAID

In partnership with Drugs for Neglected Diseases initiative (R21AI141227), and with collaborators at CSIC (Granada, Spain; R01AI114685) and Kennesaw State University (R01AI124046), we will repurpose human kinase inhibitors as treatments for the parasitic diseases leishmaniasis, Chagas disease and human African trypanosomiasis.

11/12/2020

Geoffrey Trussell

MES
|
Sponsor: NSF

Collaborative Research: Adaptation and the resiliency of food web structure and functioning to climate change

11/12/2020

Geoffrey Trussell

MES
|
Sponsor: NSF

Local adaptation and the evolution of plasticity under predator invasion and warming seas: consequences for individuals, populations, and communities.

11/12/2020

Laurel Gabard-Durnam

Psychology
|
Sponsor: Gates Foundation

The goal of this award is to test the efficacy of early brain imaging measures in predicting subsequent childhood cognitive outcomes across global contexts of adversity.

11/12/2020

Oleg Batichev

Physics
|
Sponsor: AFOSR

Instrumentation for High Energy-Density Plasma Facility

11/12/2020

Derek Isaacowitz

Psychology
|
Sponsor: NIH

Emotion Regulation in Adulthood and Aging: Preference and Effectiveness

11/12/2020

Alexander Ivanov

Chemistry
|
Sponsor: NIH

Robust ultra-high sensitivity proteomic technologies for limited samples

10/14/2020

Roman Manetsch

Chemistry
|
Sponsor: NIH

Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class Antimicrobials

10/14/2020

Alexandros Makriyannis

Chemistry
|
Sponsor: NIH

CB1 Neutral Antagonists for Alcohol Use Disorder

05/13/2020

Mary Jo Ondrechen

Chemistry
|
Sponsor: NSF

Undergraduate Research in Modeling and Computation for Discovery of Molecular Probes for SARS-CoV-2 Proteins

05/11/2020

Sanjeev Mukerjee

Chemistry
|
Sponsor: ARO

Tip-Enhanced and Co-Localized AFM-Raman Spectroscopy to Unveil Localized-Plasmon Promoted Direct-Charge Transfers across Nano-electrochemical Interfaces

05/08/2020

John Coley

Psychology
|
Sponsor: NSF

Collaborative Research: Designing an Educational Intervention to Address Intuitive Misconceptions about COVID-19

05/08/2020

Sheeba Anteraper

Psychology
|
Sponsor: NIH

Intrinsic Functional Architecture of Detate Muclei in Autism Spectrum

05/08/2020

Meni Wanunu

Physics
|
Sponsor: NIH

Single-cell direct RNA sequencing using electrical zero-mode waveguides and engineered reverse transcriptases

04/23/2020

Mary Jo Ondrechen

Chemistry
|
Sponsor: NSF

Identification of Chemical Probes and Inhibitors Targeting Novel Sites on SARS-CoV-2 Proteins for COVID-19 Intervention.

04/09/2020

Xuwen Zhu

Mathematics
|
Sponsor: NSF

Moduli Spaces and Geometric Microlocal Analysis

Metrics with singularities are important objects in differential geometry and arise naturally in algebraic geometry, mathematical physics, number theory, representation theory, etc. This project involves studying singular metrics using geometric microlocal analysis. The central idea is to introduce new objects, called compactifications or resolutions, to resolve the singularities. These resolutions will in turn suggest which analytic techniques need to be developed. The PI intends to use this method to study problems such as the moduli space construction of constant curvature conical metrics and its relation to vortices, hyperbolic metrics with cusps and asymptotic geometry of the compactified Riemann moduli space, and gauge-theoretic partial differential equations with singular metric background.

01/30/2020

Art Kramer

Psychology
|
Sponsor: U Pitt

Effects of Tai Chi Mind-Body Exercise on the Motoric Cognitive Risk Syndrome

01/29/2020

Rebecca Shansky

Psychology
|
Sponsor: National Institute of Health

TRPV1 signaling as a sex-specific mechanism of contextual fear generalization

01/28/2020

John Engen

Chemistry
|
Sponsor: ATPases Newco, Inc

ATPases Newco, Inc.

01/28/2020

Albert-Laszlo Barabasi

Physics
|
Sponsor: Northwestern U

Fundamental Dynamics, Predictability and Uncertainty of Scientific Discovery & Advancement

01/27/2020

Rebecca Shansky

Psychology
|
Sponsor: National Institute of Health

Supplement: Mapping mesocortical contributions to estrous-dependent learning processes

01/23/2020

Karen Quigley

Psychology
|
Sponsor: Mass General Hospital

Ovarian Effects on Intrinsic Connectivity and the Affective Enhancement Memory

01/17/2020

James Monaghan

Biology
|
Sponsor: Retina Research Foundation

Analysis of Notch signaling-mediated cell fate determination during regeneration of the neural retina

01/14/2020

Jeff Galkowski

Mathematics
|
Sponsor: National Science Foundation

Collaborative Research: Microlocal Concentration and Propagation in Spectral Theory

01/14/2020

Derek Isaacowitz

Psychology
|
Sponsor: University of Zurich

The Role of Emotional and Motivational Attention in Healthy Aging

01/07/2020

Leila Deravi

Chemistry
|
Sponsor: National Science Foundation

CAREER: Protein-integrated materials: From molecules to machines

01/06/2020

Srinivas Sridhar

Physics
|
Sponsor: Tufts

The Tufts Clinical and Translational Science Institute - Pilot - Objective Portable Diagnostics of Neurological Disorders

12/16/2019

Kim Lewis

Biology
|
Sponsor: National Institute of Health

Antibiotic discovery from environmental microorganisms of Brazil

12/10/2019

Sergey Kravchenko

Physics
|
Sponsor: National Science Foundation

Band flattening at the Fermi level as a precursor of quantum electron crystallization

12/04/2019

Albert-Laszlo Barabasi

Physics
|
Sponsor: Rockefeller Fndn

Scoping Out the Periodic Table of Food

12/04/2019

John Coley

Psychology
|
Sponsor: Tufts

Longitudinal Investigation of the Decision Process in Adoption of Course-based Research

11/27/2019

Peter Bex

Psychology
|
Sponsor: MEE

Assessing Spatial Processing Deficits in Cerebral Visual Impairment (CVI) Using Virtual Reality

11/25/2019

John Engen

Chemistry
|
Sponsor: National Institute of Health

Conformational Regulation and Therapeutic Targeting of Oncogenic KRAS

11/25/2019

Katie Lotterhos

Marine and Environmental Science
|
Sponsor: Rutgers U

Antibiotic Tolerance of Bacterial Pathogens in Cystic Fibrosis

11/22/2019

James Monaghan

Biology
|
Sponsor: Loyola U

Oculomotor Deficits and Plasticity Across Gaze Posture in Strabismus

11/20/2019

Maiya Geddes

Psychology
|
Sponsor: Brandeis U

Boston Roybal Center Pilot: Changing and understanding motivation to increase physical activity among sedentary older adults

11/15/2019

Leila Deravi

Chemistry
|
Sponsor: Office of Navy Research

A Scalable Platform for Electroresponsive Optical Displays Inspired by Cephalopods

11/15/2019

Brian Helmuth

Marine and Environmental Science
|
Sponsor: Environemntal Defense Fund

Developing a Climate Roadmap for Sustainable Fisheries in China

11/14/2019

Jared Auclair

Chemistry
|
Sponsor: Amgen

Amgen Donation Agreement for the Biopharmaceutical Analysis Training Laboratory (BATL)

11/06/2019

Lisa Barrett

Psychology
|
Sponsor: Sloan Fndn

Book Grant: Seven Insights about the Brain.

11/06/2019

John Engen

Chemistry
|
Sponsor: Genzyme

Hydrogen Deuterium Exchange Mass Spectrometry for the Analysis of Acid Sphingomyelinase

10/07/2019

Alina Marian

Mathematics
|
Sponsor: Radcliffe Institute

THE CHOW RINGS OF MODULI SPACES OF STABLE SHEAVES

10/03/2019

Steven Lopez

Chemistry
|
Sponsor: Mass Life Sciences

In Silico Design of an Array of Multicolor, Hybrid Fluorescent and Photodynamic Chromophores for Cancer Surgery and LightActivated Therapy

09/23/2019

Gregory Fiete

Physics
|
Sponsor: NSF

DMREF: Collaborative Research: Design and synthesis of novel materials for spin caloritronic devices

09/17/2019

Steven Lopez

Chemistry
|
Sponsor: NSF

Collaborative Resarch: Accelerating the Discovery of Electronic materials through Human-Computer Active Search

09/13/2019

Dan Distel

Marine and Environmental Science
|
Sponsor: NOAA

Bioprospecting for industrial enzymes and drug lead compounds in an ancient submarine forest.

09/13/2019

Jonathan Grabowski

Marine and Environmental Science
|
Sponsor: NOAA
08/19/2019

Alessandro Vespignani

Physics
|
Sponsor: NSF

Collaborative Research: AccelNet: Accelerating Discovery in Multilevel Network Science

07/26/2019

Craig Gruber

Psychology
|
$100,000
Sponsor: ARL

Congested and Contested RF Emulations with Colosseum

07/26/2019

Rhea Eskew

Psychology
|
Sponsor: NSF

Higher-Order Color: From Cones to Postreceptoral Mechanisms

07/26/2019

Aron Stubbins

Marine and Environmental Science
|
Sponsor: NSF

Collaborative Research: CBET: The role of sunlight in determining the fate and microbial impact of microplastics in surface waters

07/25/2019

Alessandro Vespignani

Physics
|
Sponsor: CDC

Multiscale modeling of layered pharmaceutical and non-pharmaceutical intervention during an emerging influenza pandemic

07/23/2019

Susan Whitfield-Gabrieli

Psychology
|
Sponsor: BIDMC

A Psychobiological Follow-up Study of Transition from Prodrome to Early Psychosis

07/22/2019

Craig Ferris

Psychology
|
Sponsor: Azevan Pharmaceuticals, Inc

A New Drug for the Treatment of Traumatic Brain Injury

07/22/2019

Alina Marian

Mathematics
|
Sponsor: NSF

Universal Series, Chow Rings, and Dualities in the Moduli Theory of Sheaves

07/18/2019

Susan Whitfield-Gabrieli

Psychology
|
Sponsor: HMS

Real-time fMRI Neurofeedback as a Tool to Mitigate Auditory Hallucinations in Patients with Schizophrenia

07/17/2019

David DeSteno

Psychology
|
Sponsor: Penn State

Nudging Empathy: Harnessing Motivation to Create Sustainable Empathic Choices

07/15/2019

Jonathan Grabowski

Marine and Environmental Science
|
Sponsor: TNC

Lenfest Ocean Grant

07/10/2019

Meni Wanunu

Physics
|
Sponsor: BWF

Uncovering genome variation in long DNA and repeat-disease biomarkers using nucleic acid-based reporters and nanopore readout

07/02/2019

Mark Williams

Physics
|
Sponsor: NIH

11th International Retroviral Nucleocapsid and Assembly Symposium

06/26/2019

Mary Ondrechen

Chemistry
|
Sponsor: NSF

D3SC: Mining for mechanistic information to predict protein function

06/21/2019

Leila Deravi

Chemistry
|
Sponsor: ARO

Soft, reconfigurable photonic systems inspired by cephalopod chromatophores: A platform to study dispersed light sensing in squid

06/20/2019

Steven Lopez

Chemistry
|
Sponsor: BWF

In Silico Design of an Array of Multicolor Chromophores for Cancer Surgery and Light-Activated Therapy

06/19/2019

Albert-Laszlo Barabasi

Physics
|
Sponsor: Scipher

SRA - Scipher

06/14/2019

Rebecca Shansky

Psychology
|
Sponsor: NIH

Mapping mesocortical contributions to estrous-dependent learning processes

06/10/2019

George O'Doherty

Chemistry
|
Sponsor: BIDMC

Targeted modification of the apramycin 2-deoxystreptamine ring to block aminoglycoside modifying enzyme-based inactivation and enhance potency against multidrug-resistant Gram-negative pathogens

05/31/2019

Steven Lopez

Chemistry
|
Sponsor: BWF

Burroughs Research Travel Grant

05/31/2019

Charles Hillman

Psychology
|
Sponsor: KUMC

Antioxidant Imaging Marker of Investigating Gains in Neurocognition in an Intervention Trial of Exercise (AIM-IGNITE)

05/24/2019

Herbert Levine

Physics
|
Sponsor: NSF

Spatial Patterning in the Progressing Tumor - The Role of Notch

05/23/2019

Alina Karma

Physics
|
Sponsor: Dartmouth College

Structure-property-processing correlations in freeze-cast Biomimetic Materials

05/21/2019

Paul Whitford

Physics
|
Sponsor: NSF

Quantifying the effects of ions and collective rearrangements during ribosome function

05/16/2019

Susan Whitfield-Gabrieli

Psychology
|
Sponsor: Sunovion Pharmaceuticals, Inc

Sponsored Research Agreement with Sunovion Pharmaceuticals, Inc.

05/15/2019

Eugene Smotkin

Chemistry
|
Sponsor: ARO

Quantum Theory and Measured Turnover Rates: Perovskite Chemical Transistors for Non-Faradaic Alkane Isomerization

05/14/2019

James Halverson

Physics
|
Sponsor: NSF

CAREER: Physics Implications of the String Landscape
via Formal Theory and Data Science

05/07/2019

Alexander Ivanov

Barnett
|
Sponsor: AB Sciex

Collaborative Agreement with AB Sciex

05/07/2019

Jennifer Bowen

Marine and Environmental Science
|
Sponsor: WHRC

Collaborative Research: TIDE: Legacy effects of long-term nutrient enrichment on recovery of saltmarsh ecosystems

05/07/2019

Scyphers, S

Marine and Environmental Science
|
Sponsor: TNC

Northeastern University’s Coastal Sustainability Institute and The Nature Conservancy Joint Coastal Sustainability Postdoctoral Fellows Program

03/28/2019

Charles Hillman

Psychology
|
Sponsor: KUMC

Antioxidant Imaging Marker of Investigating Gains in Neurocognition in an Intervention Trial of Exercise (AIM-IGNITE)

03/28/2019

Slava Epstein and Meni Wanunu

Biology/Physics
|
Sponsor: Raytheon BBN

INSPECT: In situ Phenotype Evaluation using CMOS Technology

03/25/2019

George O’Doherty

Chemistry
|
Sponsor: BIDMC

Targeted modification of the apramycin 2-deoxystreptamine ring to block aminoglycoside modifying enzyme-based inactivation and enhance potency against multidrug-resistant Gram- negative pathogens

03/13/2019

Alain Karma

Physics
|
Sponsor: NSF

NSF-BSF: DYNAMICS OF MATERIALS FAILURE

03/07/2019

Leila Deravi

Chemistry
|
Sponsor: ONR

A Scalable Platform for Electroresponsive Optical Displays Inspired by Cephalopods

03/05/2019

Paul Hand

Mathematics
|
Sponsor: NSF

CAREER: Signal Recovery from Generative Priors

03/05/2019

Sanjeev Mukerjee

Chemistry
|
Sponsor: ARO

Harvesting Localized Plasmons on Noble Metal Nanostructures for Efficient Electrochemical and Photochemical Reactions

03/04/2019

Qingying Jia

Chemistry
|
Sponsor: MTTC

The development of efficient platinum-group metal free catalysts to generate high purity hydrogen gas from water

02/27/2019

John Engen

Chemistry
|
Sponsor: Novartis

SRA – Exploration of biophysical methods to study the importance of KRAS protein flexibility in solution

02/22/2019

Roman Manetsch

Chemistry
|
Sponsor: NIH

Development of Streptothricin Class Antimicrobials as Novel Therapeutics

02/21/2019

Randall Hughes

Marine Science
|
Sponsor: NSF

Collaborative Research: Trait differentiation and local adaptation to depth within meadows of the foundation seagrass Zostera marina

02/21/2019

Michael Pollastri

Chemistry
|
Sponsor: NIH

Lead optimization of hits identified from virtual and experimental screens of multiple industrial libraries DNDi

02/18/2019

Arun Bansil

Physics
|
Sponsor: DOE; Temple University

A Center for Complex Materials from First Principles

02/15/2019

David Kimbro

Marine & Environmental Science
|
Sponsor: NSF

Collaborative Research: RAPID: Quantifying mechanisms by which Hurricane Michael facilitates a stable-state reversal on oyster reefs

02/14/2019

Mark Patterson

Marine & Environmental Science
|
$75,000
Sponsor: Schmidt Foundation

MantaRay Commercialization Strategy

02/13/2019

Kim Lewis

Biology
|
$86,711
Sponsor: ARO / Harvard

Identifying pathogenic bacteria by phenotyping individual cells

02/13/2019

David Kimbro

Marine & Environmental Science
|
$22,994
Sponsor: OSU

A Collaborative Science Program for the National Estuarine Research Reserve System: Connecting End Users Throughout the Applied Research Process Primary Sponsor: Department of Commerce

02/05/2019

Steven Scyphers

Marine & Environmental Science
|
$92,906
Sponsor: TNC

Northeastern University’s Coastal Sustainability Institute and The Nature Conservancy Joint Coastal Sustainability Postdoctoral Fellows Program

02/05/2019

Roman Manetsch

Chemsitry
|
$66,000
Sponsor: NIH / BIDMC

Plasmid Eviction as a Novel Adjunctive Antimicrobial Target

02/05/2019

David DeSteno

Psychology
|
$234,439
Sponsor: John Templeton Foundation

Academic Ideas in the Public Sphere: Teaching Scientists and Philosophers How to Communicate with the “General Reader”

02/04/2019

Samuel Scarpino

Marine & Environmental Science
|
$100,000
Sponsor: The Gates Foundation / IPRD

Development and Maintenance of a Suite of Application Programmer Interfaces (API) and Data Standards

02/01/2019

Jonathan Grabowski

Marine & Environmental Science
|
$7,500
Sponsor: Town of Essex

Feasibility Study for An Essec Bay Living Shoreline Primary Sponsor: Commonwealth of Massachusetts

01/31/2019

Peter Bex

Psychology
|
$428,451
Sponsor: NIH

Eye Movement Rehabilitation in Low Vision Patients

01/29/2019

Jonathan Grabowski

Marine Science Center
|
$84,330
Sponsor: TNC

Addressing Constraints to Shellfish Aquaculture Through Quantifying Ecosystem Services and Public Perceptions in the Northeast

01/28/2019

Kim Lewis

Biology
|
$1,687,500
Sponsor: SACF

Development of Disulfiram to Treat Lyme Disease

01/28/2019

Kim Lewis

Biology
|
Sponsor: SACF

Development of Hygromycin A to Treat Lyme Disease

01/22/2019

I Kovacs

Physics
|
Sponsor: BWF

Physics Uncovering the Organizing Principles of Genetic Interaction Networks

01/11/2019

Lisa Barrett

Psychology
|
Sponsor: John Templeton Foundation

Building Online Resources for Scientists and Philosophers Communicating with the “General Reader”

01/10/2019

Alessandro Vespignani

Physics
|
Sponsor: NIH / BCH

Development of an Open-Source and Data-Driven Modeling Platform to Monitor and Forecast Disease Activity

01/09/2019

Alexander Ivanov

Biology
|
Sponsor: Medimmune

SRA – Medimmune

01/04/2019

Rebecca Shansky

Psychology
|
Sponsor: Mindlin Foundation

Endocannabinoid Modulation of Stress Coping

01/03/2019

Dagmar Sternad

Biology
|
Sponsor: Simons Foundation

Characterization of predictive abilities in individuals with ASD using web-based interception

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