Nanoparticles Pair Photodynamic and Molecular Therapies against Pancreatic Cancer in Mice

A nanoparticle drug-delivery system tested in animal models that combines two complementary types of anticancer treatment could improve outcomes for patients with pancreatic cancer and other highly treatment-resistant tumors while decreasing toxicity.

In Nature Nanotechnology, a team of Harvard Medical School researchers based at the Wellman Center for Photomedicine at Massachusetts General Hospital described how they deployed a nanomedicine that combines photodynamic therapy—the use of light to trigger a chemical reaction—with a molecular therapy drug targeted against common treatment-resistant pathways.

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Physics