Researchers investigate four promising new Lyme disease treatments

Advances in Lyme Disease Treatment

Prof. Lewis, Lyme Disease Researcher  Prof. Kim Lewis
Uni­ver­sity Dis­tin­guished Pro­fessor Kim Lewis, who leads the Lyme Disease Treatment research team, is now expanding that ther­a­peutic reach with the help of a $1.5 mil­lion grant from the Steven and Alexandra Cohen Foundation.

Pre­venting chronic disease

“Time is of the essence. According to the Cen­ters for Dis­ease Con­trol and Pre­ven­tion, about 300,000 people are diag­nosed with Lyme dis­ease in the U.S. each year. The dis­ease is trans­mitted by ticks pri­marily car­rying the bac­terium Bor­relia burgdor­feri, though a new less preva­lent bac­te­rial species, Bor­relia may­onii, was iden­ti­fied by Mayo Clinic researchers in February.” The Lewis research group at Northeastern University are developing new Lyme Disease Treatments to combat the bacteria.

A new regimen for Lyme Disease Treatment

“Lewis and his col­leagues are providing focus to the problem of how to pre­vent the sub­se­quent rise of the chronic condition [by developing four new Lyme Disease treatments]. A sub­pop­u­la­tion of B. burgdor­feri cells, they dis­cov­ered ear­lier, are “per­sister” cells—they are alive but lie dor­mant, in a spore­like state. Because antibi­otics attack only actively func­tioning bac­te­rial cells, per­sis­ters escape the onslaught. How­ever, once the antibi­otic has been flushed from the system, the per­sis­ters “wake up,” says Lewis, dividing and mul­ti­plying until an army of progeny infect the host.” -Quoted from Thea Singer’s Northeastern University COS News Article

Biology