In a recently funded project involving Boston Children’s Hospital and Northeastern University, chemistry Professors John R. Engen and Roxana Iacob have teamed up with Prof. Timothy A. Springer—a renowned immunologist and structural biologist from Harvard Medical School (HMS) and Boston Children’s Hospital—to uncover the inner-workings of an extremely complex class of proteins.

Professor John Engen helped develop a new hybrid technique to study how a critical HIV protein changes shape to allow infected cells to evade the immune system.

Chemistry and chemical biology professor John R. Engen uses a novel technique to analyze large, complex biopharmaceutical drugs, which could have major implications for healthcare and its associated costs.