Faculty Labs

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186 Labs Found
Biomedical Optics Research Group
This group studies biomedical optics and non-invasive imaging, rare cell detection and tracking in the body, ultrafast time-domain diffuse optical imaging, image reconstruction and biomedical signal processing.
Booth Lab
The Booth lab undertakes drug developing starting with a GPCR structure-based ligand design approach using molecular modeling experiments, followed by synthesis of target ligands and in vitro molecular pharmacology assays to delineate their a nity and function.
Center for Complex Network Research (CCNR)
The Center’s objective is simple: think networks. Research focuses on how networks emerge/evolve, how they look, and how they impact our understanding of complex systems. CCNR’s research has developed to unexpected areas, including the topology of the World Wide Web; complex networks inside th..
Cram Lab
Erin Cram
The Cram Laboratory utilizes the model organism Caenorhabditis elegans as an in vivo system to examine how mechanical forces are sensed and interpreted by cells and how this influences cell migration. In  addition, they collaborate with Chemical Engineers to improve production of drug compound..
The CTNI
Work at the CTNI is focused on four major areas 1) Alzheimer’s disease, 2) Parkinson’s disease 3) repetitive mild traumatic brain injury, and 4) opioid addiction. Preclinical animal models for each of these problems in human health are studied using non-invasive magnetic resonance imaging to fo..
Day Lab
The Day Lab investigates the molecular role of G quadruplex DNA in genome stability and human disease.  
Dong Theoretical and Computational Chemistry Lab
The Dong Lab develops and applies physics-based and data-driven computational methods to understand multiscale processes, from electronic structures to emergent properties. We use such understandings to develop design strategies for molecules, materials, and processes that matter in renewable energ..
Biochemistry
Ebong Lab
The Ebong Lab studies the means by which endothelial cell mechanotransduction occurs in order to prevent or promote atherosclerosis
Nanomedicine Innovation Center (NIC)
The mission of the Nanomedicine Innovation Center is to generate cutting-edge research in Nanomedicine, develop innovative education and training, and place an emphasis on diversity and broadening participation. It is home to state-of-the art facilities and resources and has established partnership..
Engen Lab
The Engen Lab uses hydrogen exchange and mass spectrometry (HX MS) as our core technology to probe protein conformation, conformational changes, dynamics, protein folding and the effects of binding.
Geisinger Lab
The Geisinger lab investigates the molecular basis of antibiotic resistance and disease development in infections with hospital-acquired pathogens.
Godoy Lab
Veronica Godoy-Carter
The Godoy lab seeks to learn about the mechanism(s) regulating the activity of potentially mutagenic DNA polymerases.

News

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Protective salt marshes along coasts are in danger across the globe but it’s not too late to act, Northeastern researchers say

Salt marshes are among coastal habitats endangered by both rising sea levels and urban development.

Preserving and restoring salt marshes is essential not only for wildlife protection and natural flood mitigation, but also for the numerous ecosystem services — such as carbon storage, bird watching and fishing — they provide to urban dwellers.

This is the case a group of Northeastern University scientists is making in a recent study that predicts how New England salt marshes might look by 2100 due to rising sea levels, using the example of Belle Isle Marsh Reservation, Boston’s last remaining salt marsh.

The scientists suggest potential actionable solutions that can help preserve the marsh.

“I don’t think it’s too late to act,” says Jahson Alemu I, who led the study and worked closely with municipalities and communities that border the marsh as a postdoctoral fellow of the Coastal Sustainability Institute, a joint program between the Marine Science Center at Northeastern and the Nature Conservancy, a global environmental nonprofit.

Read more from Northeastern Global News

Photo by Alena Kuzub/Northeastern University

December 16, 2024
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The interaction between humans and artificial intelligence demands a new field of study, Northeastern researchers say

To be an internet user in 2024 is like being a hamster running on a wheel. The modern web is largely composed of consumer services that use artificial intelligence-based algorithms to hook people to stay logged on — for better and for worse.

“You as a user make choices,” says Tina Eliassi-Rad, a computer sciences professor at Northeastern University and a core faculty member of the Northeastern Network Science Institute and the Institute for Experiential AI.

“You watch certain things. You buy certain things. You’re producing training data for these AI algorithms, specifically recommendation systems — think Amazon, think Netflix, think Match.com”

“These AI algorithms produce suggestions to you, those suggestions supposedly influence your choices,” she adds. “Through that, you’re producing more training data for the algorithm, and round and round we go.”

In essence, the web is made up of a series of human and AI feedback loops correlated with user behavior, Eliassi-Rad explains.

Eliassi-Rad is one of several Northeastern researchers who have proposed a new area of study they are calling “Human AI Coevolution” to better understand and analyze these feedback loops. Other researchers on the project include Northeastern professors Ricardo Baeza-YatesAlbert-László Barabási and Alessandro Vespignani.

Read more from Northeastern Global News

Photos by Ruby Wallau, Matthew Modoono/Northeastern University and courtesy photo

December 16, 2024

Northeastern researchers find a faster and more sensitive way to study proteins, which could lead to advances in disease treatment

Protein complexes are important for the majority of vital processes in the cell and human body, such as producing energy, copying DNA and regulating the immune system.

Composed of groups of connected protein chains called subunits, the complexes are also good targets for medicines that treat diseases.

But studying them in their native, natural physiological state, while preserving their 3-D protein folds, has proved challenging.

Traditional mass spectrometry methods and structural biology techniques may require breaking protein chains into pieces or turning protein parts into crystals.

These approaches not only disrupt the structure of the assembled protein molecules but involve using substantial amounts of samples and waiting weeks for results.

Now researchers at Northeastern University have developed a novel method of preserving the structure of protein complexes and their interactions under near-native conditions while analyzing them in 30 minutes or less, using small sample amounts.

Associate research scientist Anne-Lise Marie and associate professor of chemistry and chemical biology Alexander R. Ivanov say their research, published in the Advanced Science journal, could eventually expedite drug development for pathologies such as Alzheimer’s and Parkinson’s disease.

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Photo by Alyssa Stone/Northeastern University

December 13, 2024

Why are axolotls suddenly so popular — and going extinct at the same time?

You may have seen axolotls — an amphibian in the salamander family with a permanent smile and pink, feathery gills — in a pet store or as a plushie in a window, but the endearing animal’s popularity seems to be rising just as it has become critically endangered in the wild.

James Monaghan, professor of biology at Northeastern University, specializes in the friendly looking critters, studying their amazing regenerative capabilities. “Axolotls have just exploded in [popularity] the past couple of years,” he says.

Read more from Northeastern Global News

Photo by Alyssa Stone/Northeastern University

December 13, 2024

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