Faculty Labs

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186 Labs Found
The Ionescu Lab
Our research centers on skeletal development and pathology with an emphasis on tissue regeneration and repair after injury.  We aim to fate map how skeletal stem cells contribute to the growth of the skeletal elements during development via mouse transgenesis, lineage tracing and single cell trans..
The Kwon Lab for Low Vision and Brain Research
Welcome to the Kwon Lab for Low Vision and Brain research! Our lab is based in the Department of Psychology at Northeastern University. The central theme of research in our lab is to understand how people with visual impairment see and recognize the world around them. To this end, we study how the ..
Lewis Lab
The Lewis Lab studies persister cells responsible for tolerance to antibiotics, uncultured bacteria of the environment and the microbiome, and works on drug discovery.
Manetsch Lab
The Manetsch laboratory addresses various aspects of medicinal chemistry related to optimization of anti-malarial, anti-leishmanial, and anti-bacterial agents., as well as developing and applying LC/MS-based approaches facilitating synthetic and medicinal chemistry.
Mattos Lab
Research in the Mattos Lab focuses on understanding the rules that govern the recognition, assembly and function of macromolecular complexes.
Miller Lab
Greg Miller's lab focuses on the neurobiology, immunology and genetics associated with acute and chronic exposure to drugs of abuse. Their goals are to understand how drugs of abuse work in the brain and the body, to create new pharmacological treatment strategies for people who are addicted and mo..
Monaghan Lab
James Monaghan
Dr. Monaghan’s lab uses the axolotl salamander to investigate the cellular and molecular basis of complex tissue regeneration. Axolotls have the amazing ability to regenerate large portions of their limbs, tail, heart, and spinal cord. His lab studies the development and regeneration of the nervo..
O’Doherty Group
This research group has been working in two related areas of organic synthesis: carbohydrate synthesis and natural product synthesis.  The unifying theme that connects the research in these two areas is the method of synthesis (asymmetric catalysis) and target selection (anti-cancer, anti-viral an..
Research Alliance in Science and Engineering (RAISE)
Through integrative education and collaboration between undergraduate chemistry students and faculty mentors, RAISE continues the teaching curriculum beyond the classroom and into the real world.
Zhang Group
The Zhang group develops macromolecular systems to provide answers to important questions in biology and medicine.
Theoretical Particle Physics Group
Members of our group work in particle physics, cosmology, and string theory, often with overlap between the subjects.
Theoretical Photochemistry
The Lopez group uses quantum mechanical and machine learning techniques to identify next-generation organic materials for applications in renewable energy and photomedicine.

News

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Protective salt marshes along coasts are in danger across the globe but it’s not too late to act, Northeastern researchers say

Salt marshes are among coastal habitats endangered by both rising sea levels and urban development.

Preserving and restoring salt marshes is essential not only for wildlife protection and natural flood mitigation, but also for the numerous ecosystem services — such as carbon storage, bird watching and fishing — they provide to urban dwellers.

This is the case a group of Northeastern University scientists is making in a recent study that predicts how New England salt marshes might look by 2100 due to rising sea levels, using the example of Belle Isle Marsh Reservation, Boston’s last remaining salt marsh.

The scientists suggest potential actionable solutions that can help preserve the marsh.

“I don’t think it’s too late to act,” says Jahson Alemu I, who led the study and worked closely with municipalities and communities that border the marsh as a postdoctoral fellow of the Coastal Sustainability Institute, a joint program between the Marine Science Center at Northeastern and the Nature Conservancy, a global environmental nonprofit.

Read more from Northeastern Global News

Photo by Alena Kuzub/Northeastern University

December 16, 2024
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The interaction between humans and artificial intelligence demands a new field of study, Northeastern researchers say

To be an internet user in 2024 is like being a hamster running on a wheel. The modern web is largely composed of consumer services that use artificial intelligence-based algorithms to hook people to stay logged on — for better and for worse.

“You as a user make choices,” says Tina Eliassi-Rad, a computer sciences professor at Northeastern University and a core faculty member of the Northeastern Network Science Institute and the Institute for Experiential AI.

“You watch certain things. You buy certain things. You’re producing training data for these AI algorithms, specifically recommendation systems — think Amazon, think Netflix, think Match.com”

“These AI algorithms produce suggestions to you, those suggestions supposedly influence your choices,” she adds. “Through that, you’re producing more training data for the algorithm, and round and round we go.”

In essence, the web is made up of a series of human and AI feedback loops correlated with user behavior, Eliassi-Rad explains.

Eliassi-Rad is one of several Northeastern researchers who have proposed a new area of study they are calling “Human AI Coevolution” to better understand and analyze these feedback loops. Other researchers on the project include Northeastern professors Ricardo Baeza-YatesAlbert-László Barabási and Alessandro Vespignani.

Read more from Northeastern Global News

Photos by Ruby Wallau, Matthew Modoono/Northeastern University and courtesy photo

December 16, 2024

Northeastern researchers find a faster and more sensitive way to study proteins, which could lead to advances in disease treatment

Protein complexes are important for the majority of vital processes in the cell and human body, such as producing energy, copying DNA and regulating the immune system.

Composed of groups of connected protein chains called subunits, the complexes are also good targets for medicines that treat diseases.

But studying them in their native, natural physiological state, while preserving their 3-D protein folds, has proved challenging.

Traditional mass spectrometry methods and structural biology techniques may require breaking protein chains into pieces or turning protein parts into crystals.

These approaches not only disrupt the structure of the assembled protein molecules but involve using substantial amounts of samples and waiting weeks for results.

Now researchers at Northeastern University have developed a novel method of preserving the structure of protein complexes and their interactions under near-native conditions while analyzing them in 30 minutes or less, using small sample amounts.

Associate research scientist Anne-Lise Marie and associate professor of chemistry and chemical biology Alexander R. Ivanov say their research, published in the Advanced Science journal, could eventually expedite drug development for pathologies such as Alzheimer’s and Parkinson’s disease.

Read more from Northeastern Global News

Photo by Alyssa Stone/Northeastern University

December 13, 2024

Why are axolotls suddenly so popular — and going extinct at the same time?

You may have seen axolotls — an amphibian in the salamander family with a permanent smile and pink, feathery gills — in a pet store or as a plushie in a window, but the endearing animal’s popularity seems to be rising just as it has become critically endangered in the wild.

James Monaghan, professor of biology at Northeastern University, specializes in the friendly looking critters, studying their amazing regenerative capabilities. “Axolotls have just exploded in [popularity] the past couple of years,” he says.

Read more from Northeastern Global News

Photo by Alyssa Stone/Northeastern University

December 13, 2024

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