Grants

Society significantly benefits from scientific research, but it wouldn’t be possible without generous contributions from public and private sources.

This page is a testament to that support. With it, Northeastern’s College of Science has cultivated a dynamic landscape of research activity. Through a culture that emphasizes entrepreneurship, our exceptional faculty, staff, and student researchers are able to maximize the impact of their work.

The grants listed below are a preview of the science and scientists of tomorrow, who probe single cells, the outer limit of particle physics, and everything in between.

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  • 2023

    Needa Brown

    Sponsor: DFCI
    STING agonist drug delivery formulations synergize with PARPi to treat resistant, metastatic advanced breast cancer The objective of this work is to generate clinically relevant data to support the use of PARPi in combination with local and systemic drug delivery platforms of STING agonists in order to treat metastatic, resistant breast cancer.Read More
  • 2023

    Philip Deming

    Sponsor: NIH
    Probing negative affect circuits in humans using 7T fMRI Negative mood is a common feature of anxiety, depression, bipolar disorder, and schizophrenia, which inflict immeasurable human suffering along with a combined economic burden of $600 billion in the US each year. The proposed research promises to deliver a new paradigm for studying the brain basis…Read More
  • 2023

    Katie Lotterhos

    Sponsor: U Gothenburg
    A seascape of adaptations – Testing models that predict performance in multivariate environments We are studying the adaptation of eelgrass to future ocean conditions in the Baltic Sea.Read More
  • 2023

    Sijia Dong

    Sponsor: NSF
    Collaborative Research: Enzyme-Mimicking Catalysts for Cellulose Processing Lignocellulosic biomass from plants is a renewable, carbon-neutral material produced at a scale of 170-200 billion tons per year. The depolymerization of cellulose is a key step in biomass conversion, but it is challenged by the stability and crystalline nature of the cellulose fibers. We will develop synthetic…Read More
  • 2023

    Bryan Spring

    Sponsor: NIH
    Fractionated photoimmunotherapy to harness low-dose immunostimulation in ovarian cancer The Spring research group, in collaboration with the Enderling lab at Moffit Cancer Center, has been awarded a Physical Sciences Oncology Network grant (NCI U01 CA280849; ~$2.7M) titled “Fractionated photoimmunotherapy to harness low-dose immunostimulation in ovarian cancer”. The project will harness an integrated experimental—mathematical oncology approach to…Read More
  • 2023

    Herbert Levine

    Sponsor: NSF
    DMS/NIGMS 2: Regulation of Cellular Stemness during the Epithelial-Mesenchymal Transition (EMT) We propose a joint theoretical/experimental research program to address cell-fate trajectories that occur during induction of EMT, the epithelial-mesenchymal transition. Specifically. recent efforts have indicated that epithelial cells can either undergo direct reprogramming to mesenchymal states or alternatively become more stem-like and exhibit hybrid…Read More
  • 2023

    Susanne Jaeggi & Aaron Seitz

    Sponsor: Department of Defense (DoD), Office of Naval Research (ONR), Multidisciplinary University Initiative (MURI) #WU-24-0185 (NU sub: ST00019438)
    A Computational Cognitive Neuroscience Framework for Attentional Control Traits and States In this collaborative project that involves groups from Washington University (St. Louis), Brown University, University of California, Irvine, as well as several groups in Australia, we develop tools / apps to assess attention control in high-performing adults (e.g. pilots or air-traffic controllers) using computational…Read More
  • 2023

    Valerio Toledano Laredo

    Sponsor: NSF
    Transcendental fiber functors, shift of argument algebras and Riemann-Hilbert correspondence for q-difference equations This project stems from the recent discovery that quantum groups naturally arise from the Stokes data of differential equations associated to classical symmetries. The main goals are to further explore this bridge between classical and quantum symmetries. Of particular interest is the…Read More
  • 2023

    Xuwen Zhu

    Sponsor: NSF
    Microlocal analysis and singularities Degenerations and singularity formations play important roles in the study of differential geometry and arise naturally in multiple other areas of mathematics, including, algebraic geometry, mathematical physics, number theory, and representation theory. This project concerns the geometry of singularities and has interesting connections with an array of disciplines including modeling of…Read More
  • 2023

    Roman Manetsch

    Sponsor: NIH
    Activation of Benzoxaborole Prodrug AN15368, a Clinical Candidate for Chagas Disease Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is endemic in the Americas, but has also globalized due to human migration. Despite being one of the major causes of infection-induced heart disease worldwide, current therapies for Chagas disease have inconsistent efficacy and frequent…Read More
  • 2023

    Meni Wanunu

    Sponsor: NIH
    Unidirectional single-file transport of full-length proteins through a nanopore In this multi-PI project between the Wanunu Lab (Northeastern), Chen Lab (UMass Amherst), Aksimentiev Lab (Urbana Champaign), and Niederweis Lab (U Alabama), we will develop a next-generation single-molecule protein sequencer based on engineered high-resolution nanopores. Key reference to cite: Yu et al., Unidirectional single-file transport of…Read More
  • 2023

    Qimin Yan

    Sponsor: DOE
    Synthesis of motif and symmetry for accelerated learning, discovery, and design of electronic structures for energy conversion applications The goal of the proposed work is to develop the data-driven approach based on structure motifs and orbital symmetries to discovery and design inorganic semiconductor compounds with optimal electronic structures for energy conversion applications. Objectives are: (i)…Read More

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