Stem Cells and Regeneration
Research in this area studies cells capable of self-renewal and differentiation into specialized cell types and investigates tissue repair and organ development mechanisms. Through this research, our scientists can explore therapeutic applications for treating injuries, degenerative diseases, and organ failure through cell-based therapies, tissue engineering, and understanding developmental processes that enable biological regeneration.
Members
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Dr. Ionescu’s research centers on skeletal development and pathology with an emphasis on tissue regeneration and repair after injury.
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The Monaghan Lab uses the axolotl salamander to investigate the cellular and molecular basis of complex tissue regeneration for potential application to human injury and disease treatment.
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The Moore Bone Lab utilizes novel investigative tools to identify new strategies for forming mineralized tissue when and where it is needed in patients of all ages.
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Dr. Santos aims to uncover how bacteria manufacture and install stabilizing protein entities into cell walls, which could form the basis of new antibiotics.
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Dr. Tilly investigates genetic and epigenetic drivers of cell lineage specification, differentiation, and death to develop innovative technologies that improve human health within and across generations.
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The Wang Lab develops mammalian synthetic biology tools to advance anti-cancer cellular therapy, regenerative medicine, and microfluidic human organ models.
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Dr. Woods studies the role of mitochondria in normal and disease states, with a major emphasis on female reproductive function and health.
Interested in working with us?
In the news
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Research
How do axolotls regenerate limbs and organs? This researcher has started to uncover the secret
New research by James Monaghan, professor of biology, shows that the key to axolotl limb regeneration is retinoic acid. Could this be the key to human limb regeneration in the future? -
Research
New Northeastern research could revolutionize treatment for children’s growth plate fractures using stem cells
Andreia Ionescu, assistant professor of biology, is conducting research to understand how stem cells can be used to treat bone fractures. -
New Northeastern lab plumbs the mysteries of the ticks and bacteria that cause Lyme
Constantin Takacs of Northeastern loves to study black-legged deer ticks and Borrelia burgdorferi, which is good news for everybody else -
A Northeastern-led team is uprooting modern reproductive biology
A March 2022 study from the two Northeastern biology professors’ labs, spearheaded by biology Ph.D. students Hannah Alberico and Zoe Fleischmann, further affirmed the existence of ovarian stem cells in humans, indicating humans may not have a fixed number of eggs from birth and that the body is capable of producing more. The discovery turns modern reproductive biology on its head.