Constantin (Nick) Takacs

Constantin (Nick) Takacs

Assistant Professor


  • Cell Biology, Genetics, Tick Biology, Microbiology

About Constantin (Nick) Takacs

The Takacs lab opened at Northeastern University in the Biology Department in January 2023. We will be studying the Lyme disease bacterium, Borrelia burgdorferi, its tick vector, and their interactions though a set of genetic, imaging, and biochemical approaches.

Nick Takacs obtained his Ph.D. in 2016 from Rockefeller University where he studied hepatitis C virus, lipoprotein secretion, and liver diseases with Drs. Sanford M. Simon and Charles M. Rice. He then pursued postdoctoral research with Dr. Christine Jacobs-Wagner at Yale University, Stanford University and HHMI. During his postdoc, Nick developed genetic methods for use in the Lyme disease bacterium Borrelia burgdorferi, including a highly efficient and easy to use CRISPRi-based gene expression knockdown method. Nick also visualized the polyploid and highly-segmented genome of Borrelia burgdorferi, and identified a new mechanism of bacterial chromosome segregation.

Nick is committed to mentorship and to fostering a collaborative, inclusive, and supportive research environment. Trainees from all backgrounds are welcome!



Mailing Address:

360 Huntington Ave. 206H Mugar Life Sciences Bldg. Boston, MA 02115


Your Tomorrow Starts Here.Learn More Today.