About Constantin (Nick) Takacs
The Takacs lab opened at Northeastern University in the Biology Department in January 2023. We will be studying the Lyme disease bacterium, Borrelia burgdorferi, its tick vector, and their interactions though a set of genetic, imaging, and biochemical approaches.
Nick Takacs obtained his Ph.D. in 2016 from Rockefeller University where he studied hepatitis C virus, lipoprotein secretion, and liver diseases with Drs. Sanford M. Simon and Charles M. Rice. He then pursued postdoctoral research with Dr. Christine Jacobs-Wagner at Yale University, Stanford University and HHMI. During his postdoc, Nick developed genetic methods for use in the Lyme disease bacterium Borrelia burgdorferi, including a highly efficient and easy to use CRISPRi-based gene expression knockdown method. Nick also visualized the polyploid and highly-segmented genome of Borrelia burgdorferi, and identified a new mechanism of bacterial chromosome segregation.
Nick is committed to mentorship and to fostering a collaborative, inclusive, and supportive research environment. Trainees from all backgrounds are welcome!
The Takacs Laboratory of Spirochete and Vector Biology studies the Lyme disease bacterium, Borrelia burgdorferi, its tick vector, and their interactions though a set of genetic, imaging, and biochemical approaches.