Meni Wanunu

Sponsor: NIH

Unidirectional single-file transport of full-length proteins through a nanopore

In this multi-PI project between the Wanunu Lab (Northeastern), Chen Lab (UMass Amherst), Aksimentiev Lab (Urbana Champaign), and Niederweis Lab (U Alabama), we will develop a next-generation single-molecule protein sequencer based on engineered high-resolution nanopores. Key reference to cite: Yu et al., Unidirectional single-file transport of full-length proteins through a nanopore, Nature Biotechnology, 2023. DOI: https://doi.org/10.1038/s41587-022-01598-3