Faculty Labs and Research

The research program in the Laboratory for Neglected Disease Drug Discovery focuses on those areas of research that will impact on treatment of human disease and on areas that will expedite the drug discovery process.

The Beuning Laboratory at Northeastern is focused on understanding the structure-function-dynamics relationships of proteins and enzymes, with a particular focus on proteins involved in DNA metabolism and DNA damage tolerance.

The Biomaterials Design Group works at the interface of bio-analytical chemistry, materials science, and design. We investigate fundamental mechanisms behind systems in biology and use our understanding to better inform the design new classes of protein-based biomaterials that may interface with or enhance the performance of humans.

The Engen Lab uses hydrogen exchange and mass spectrometry (HX MS) as our core technology to probe protein conformation, conformational changes, dynamics, protein folding and the effects of binding.

The Thakur Lab’s research has a multi-dimensional aspect with a focus on treating a plethora of diseases and disorders. They target receptors like cannabinoid, nicotinic, and other protein complexes with the intent of designing pharmacotherapy for Alzheimer’s disease, schizophrenia, anorexia nervosa, glaucoma, obesity, and post-traumatic stress disorder.

Professor Wanunu’s research involves studying biosystems at the nanoscale (macromolecular and sub-molecular levels).

The Zhang Group develops macromolecular systems to provide answers to important questions in biology and medicine.

SunnyLand applies protein chemistry, analysis and engineering to biology and medicine.

Our lab studies how the brain regulates aging and resilience at the cellular, tissue, and whole-organism levels in the nematode C. elegans. We use new enabling technologies, including live imaging of protein oxidation and automated lifespan measurement. Our work is interdisciplinary, combining molecular genetics, quantitative microscopy, mathematical modeling, and engineering. We aim to uncover fundamental […]

NeuroLab focuse on a new invertebrate model for central nervous system regeneration and the development of advanced devices for microscopy and imaging.

The focus of the Advanced Biomaterials for Neuroengineering Laboratory (ABNEL) is developing novel and transformative devices, biomaterials, and biophysical-based therapies for neuropathies in the Central, Peripheral, and Enteric nervous systems.

The Woods Laboratory is interested in studying the role of mitochondria in normal and disease states, with a major emphasis on female reproductive function and health.