Philip Deming

Sponsor: NIH

Probing negative affect circuits in humans using 7T fMRI

Negative mood is a common feature of anxiety, depression, bipolar disorder, and schizophrenia, which inflict immeasurable human suffering along with a combined economic burden of $600 billion in the US each year. The proposed research promises to deliver a new paradigm for studying the brain basis of negative affect, with the ultimate goal of developing targeted treatments for negative mood, a hallmark feature of many mental illnesses.