Eddie Geisinger

Sponsor: NIH

Repurposing Gram-positive Antibiotics for Gram-Negative Bacteria using Antibiotic Adjuvants 

The multidrug-resistant (MDR) sepsis pathogen Acinetobacter baumanni presents an enormous ongoing challenge to public health. Current treatment options for infections with these bacteria are extremely limited. Our research examines a class of small molecules called antibiotic adjuvants that greatly boost the activity of several existing antibiotics against A. baumanniim, with the goal of developing new combination approaches to treat MDR infections.