Khrapko Laboratory

Khrapko’s Lab is studying mutations in mtDNA and their effects on cellular physiology, aging and disease. They also use mtDNA mutations to trace mtDNA lineages and to study human evolution.

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  • Konstantin Khrapko

    mtDNA Mitochondria are cellular organelles responsible for ATP production as well as many other cellular processes,  from calcium homeostasis to apoptosis.  Mitochondria are the only animal organelle that carries its own genome, mtDNA. mtDNA suffers high levels of somatic mutations which are suspected of being involved in aging and carcinogenesis. We are studying mutations in […]