Faculty Labs and Research

The Geisinger Lab investigates the molecular basis of antibiotic resistance and disease development in infections with hospital-acquired pathogens.

The Day Lab investigates the molecular role of G quadruplex DNA in genome stability and human disease.  

Khrapko’s Lab is studying mutations in mtDNA and their effects on cellular physiology, aging and disease. They also use mtDNA mutations to trace mtDNA lineages and to study human evolution.

Dr. Tilly’s lab seeks to promote a deeper understanding of the genetic and epigenetic drivers of cell lineage specification, differentiation and death, and to then utilize the information gained from these studies for development of innovative new technologies to improve human health within and across generations.

The Institute develops imaging tools to highlight chemical processes – enabling clinicians to better diagnose and treat disease.

The Center translates basic discoveries into novel antimicrobial therapies to help resolve the Antimicrobial Resistance Crisis, a slow-moving pandemic, according to the WHO. combat Biowarfare and conventional pathogen threats. The Center is funded by grants from the NIH, The Schmidt Futures and the Steven & Alexandra Cohen Foundation.

This institute focuses on the role of tissue inflammation in fighting disease and infection, and the mechanisms that control tissue inflammation in the body. The Institute’s work has immediate implications for anti-cancer strategies and approaches to improved vaccines.

The Ionescu Lab studies skeletal development, pathology, and regeneration, focusing on stem cell fate mapping, lineage tracing, and single-cell transcriptomics to uncover mechanisms of skeletal growth and repair.

The Sive Lab, led by Hazel Sive, studies the development of the vertebrate embryo. The group has made unique contributions to the fundamental questions of how the face forms and how the brain develops its normal structure. Research in the Sive Lab emphasizes neurodevelopmental and craniofacial disorders. The group uses the accessible frog and zebrafish models, as […]

The Interdisciplinary Affective Science Laboratory (IASL) studies emotions what they are, and how they work— using experiential, behavioral, psychophysiological, and brain-imaging techniques. The IASL is located at Northeastern University, with a secondary site at Mass General Hospital.

The Takacs Laboratory of Spirochete and Vector Biology studies the Lyme disease bacterium, Borrelia burgdorferi, its tick vector, and their interactions though a set of genetic, imaging, and biochemical approaches.

The Saavedra Lab investigates host-microbe interactions in health and disease through an immunology and cell biology lens.