Bilyana Koleva

PhD Profile: Bilyana Koleva

Bilyana Koleva, a Chemistry PhD candidate, sits down with the College of Science Graduate Program staff to talk about what it’s like to work and study at Northeastern University.

Describe your research.

In the Beuning laboratory my research focuses on the cellular responses to DNA damage and the dynamics of the proteins involved in DNA replication and repair. One of my current research projects is understanding the influence of the dynamics of the Escherichia coli beta clamp, a ring-shaped protein responsible for the high efficiency of DNA replication and for controlling traffic on DNA.

My first doctoral project was a collaboration effort to elucidate the mechanism of action of oxazolidinones, a class of antibiotics currently active against gram-positive bacteria and to optimize their properties for activity against gram-negative bacteria since multidrug-resistant bacteria are an urgent threat.

What is your favorite part about Northeastern?
One of my favorite aspects about Northeastern is its transformative experience. Students are immersed in experiential education, realizing their academic potential while being challenged early on with real world responsibilities. Through intellectual and personal growth, Northeastern students emerge well equipped to follow their purpose in life.

Why did you choose Northeastern?
I first chose Northeastern for the opportunity to participate in experiential education during my undergraduate studies and gain valuable research experience needed in today’s job market. I engaged in the Biochemistry Club, participated in undergraduate research on campus and went on Co-op at a pharmaceutical company. Northeastern solidified my interest in being a scientist. I graduated and was eager to take on a lot of responsibilities and learn from true innovators so I landed a position at a biotechnology startup making enzymes for the next-generation sequencing market. My employer supported my drive for learning and growth and I enrolled in Northeastern’s master’s program because of the flexibility it offered for busy professionals. Finally, after completing my MS degree in Chemistry, I decided to return to Northeastern and my undergraduate research lab for my doctoral studies because of my advisor’s unwavering support. She is interested in developing critical thinkers and dedicates her time to be invested in the success of her students. In addition, the Department of Chemistry is not only a supportive and collaborative environment to do research in but also the leadership is devoted to improving graduate school life and I am very proud to be a part it.

What is your favorite part of Boston?
I like being on water as much as possible. Some of my favorite running routes include the leafy path on the Charles River Esplanade in spring and fall, the Boston waterfront from Charlestown through the North End to the Seaport, the nature walks on the Boston Harbor islands with stunning views of the city skyline and sunsets worth a visit.

What are the perks of being a Northeastern graduate student?
I’ve had the privilege to teach and mentor some outstanding undergraduates. They’ve come from all corners of the world and bring their unique experiences but they are all motivated and continue to impress me with their involvement and ambition for achievement. It’s motivational and inspirational, I am so proud to witness their growth and see them realize their potential.

What advice would you give to an incoming graduate student?
I’ve found that the sooner I committed fully and whole-heartedly, mentally and spiritually, the more I enjoyed the process. I was prepared to work long hours but the magic is to make those hours productive. Expect to troubleshoot indefinitely and accept ambiguity as part of your daily existence but as long as you are willing and able to be driven by the need to know and understand why, you will succeed. Never lose that youthful optimism and ambition you came in with.

What are your plans after degree completion?
I plan on obtaining an industrial position in a collaborative research environment solving challenging problems and coming up with creative solutions. I also would like to be able to incorporate science education and mentorship as I find this experience extremely rewarding.

Bilyana Koleva, chemistry PhD candidate

Bilyana Koleva, chemistry PhD candidate

College of Science