Graduates of the PlusOne receive a Bachelor of Science degree with a major in biochemistry, biology, biotechnology, or chemistry and chemical biology followed by a Master of Science (MS) degree in biotechnology.

Thirty-four graduate credits are required in the PlusOne program; half of these (17 SH) can be taken as an undergraduate.

In essence, a fixed series of prescribed courses taken as an undergraduate replaces most of the science electives taken for the BS. Once the student graduates with his/her BS, the student becomes a full-time graduate student, enrolling in the same courses as other second year graduate students in the PSM program, and taking a minimum of 17 credits of graduate courses.