Technology

The Center for Advanced Regulatory Analysis provides analytical services based on a large array of state-of-the-art instrumentation and world class technical staff.

CARA also evaluates the capabilities of existing analytical technologies on behalf of tool providers by conducting cross-platform evaluation. The Center participates in the creation of new or improved analytical technologies and provides independent analyses of drugs produced in the U.S. and overseas and also conducts comprehensive characterization studies of complex glycoproteins.

Below is a sample:

  • AB Sciex 5800 MALDI ToF-ToF
  • Agilent 6330 XCT Ultra Plus Ion trap*
  • Agilent 6460 Triple Quad* w/ 1200 HPLC
  • Agilent 6520 Q-ToF* w/ 1200 HPLC
  • Agilent 6890 GC w/5973 MSD

* These systems have Agilent Chip Cube nanoESI interface

  • Thermo LTQ Fleet
  • Thermo LTQ XL Orbitrap w/ETD
  • Thermo LTQ XL Ion trap w/ETD
  • Thermo Q-Exactive w/Ultimate 3000
  • Thermo Q-Exactive Plus
  • Thermo Orbitrap Fusion Lumos w/ Ultimate 3000 UHPLC
  • Thermo Q-Exactive HF-X w/ Ultimate 3000 UHPLC
  • Bruker Solarix XR FTMS

* All systems have nanoLC systems

  • Waters Q-ToF Ultima
  • Waters Q-ToF Premier
  • Waters LCT Premier XE oa-ToF
  • Waters Synapt G1 HDMS Q-ToF
  • Waters Synapt G2 HDMS Q-ToF

* All systems have nanoACQUITY UPLC systems

  • (3) Beckman Coulter CESI 8000 Plus CE Systems

* These systems have mass spectrometer interfaces for CE-MS experiments